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Industrial Academic Initial Training Network towards specific diagnosis and treatment of age-related gait and balance deficits

Industrial Academic Initial Training Network towards specific diagnosis and treatment of age-related gait and balance deficits

Objective

Balance and gait deficits are ubiquitous among the older population, and lead to enormous personal, occupational and health care burden. Emerging pharmacological and non-pharmacological interventions to date have only small to moderate effects on these deficits. This is likely due to remaining fundamental questions on underlying mechanisms and treatment. The present project Keep Control consists of a rare EU-wide combination of experts from clinical, biomechanic and neuroscience research, along with experts from the industry, who all aim at gaining a better understanding and treatment of balance and gait deficits in older adults. We aim to scrutinize aspects such as: (1) comparability of balance and gait assessment in the clinic and the home environment, (2) gait and balance deficits as prodromal markers of neurodegeneration, and as markers to differentiate between Parkinsonian syndromes, (3) association between freezing of gait and balance, and (iv) gait and balance deficits in patients with sarcopenia. Tools such as sophisticated lab-based gait and balance assessment devices, perturbation treadmill, wearable devices, electrophysiology and blood and tissue investigations will be implemented. We will further employ promising therapeutic strategies for specific gait and balance deficits in older adults, including both pharmacologic and non-pharmacologic strategies. An entire work package will be dedicated to a novel harmonization and integration approach across the whole network: It will (i) harmonize assessment protocols based on the WHO definition of health and disability, to pave the way for an exhaustive meta-analysis of all data collected, and (ii) foster the active involvement of all study participants by implementation of a participant-controlled medical record. In summary, Keep control will cover the entire range of expertise necessary and utilize cutting edge technology to educate fellows in the area of gait and balance deficits in older adults.
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Coordinator

CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL

Address

Olshausenstrasse 40
24118 Kiel

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 436 128,84

Participants (11)

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KATHOLIEKE UNIVERSITEIT LEUVEN

Belgium

EU Contribution

€ 250 560

UNIVERSITY OF NEWCASTLE UPON TYNE

United Kingdom

EU Contribution

€ 273 287,88

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

Germany

EU Contribution

€ 249 216,48

UNIVERSIDADE DO PORTO

Portugal

EU Contribution

€ 238 356,36

STICHTING VU

Netherlands

EU Contribution

€ 255 374,28

ACADEMISCH ZIEKENHUIS GRONINGEN

Netherlands

EU Contribution

€ 255 374,28

CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE

France

EU Contribution

€ 262 875,60

MOTEK MEDICAL B.V.

Netherlands

EU Contribution

€ 255 374,28

GAIT UP SA

Switzerland

EU Contribution

€ 265 226,76

HASOMED HARD-UND SOFTWARE FUER MEDIZIN GESELLSCHAFT MBH

Germany

EU Contribution

€ 249 216,48

PATIENTS KNOW BEST LIMITED

United Kingdom

EU Contribution

€ 68 321,97

Project information

Grant agreement ID: 721577

Status

Ongoing project

  • Start date

    1 March 2017

  • End date

    28 February 2021

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 059 313,21

  • EU contribution

    € 3 059 313,21

Coordinated by:

CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL

Germany