CORDIS
EU research results

CORDIS

English EN
Chemically and Thermally Stable Nano-sized Discrete Organic Cage Compounds

Chemically and Thermally Stable Nano-sized Discrete Organic Cage Compounds

Objective

Shape-persistent organic cage compounds consisting only of covalent bonds are fascinating synthetically targets, because they are studied as hosts for the selective recognition of guest molecules, such as artificial lectins, for catalysis in confined space or for the construction of a new type of porous material. For the latter, the shape-persistency and rigidity of the cage cavity is of utmost importance. There are in principle two existing strategies for the synthesis of shape-persistent organic cage compounds. Strategy I: A stepwise approach by irreversible reactions. Here, the advantage is the chemical stability of the target compound due to the intrinsic stabilities of the formed bonds. The disadvantage of this approach is in general the low overall yield, because the system does not allow any ‘self-correction’ of once formed bonds. This is different for the other approach used in Strategy II: By using dynamic covalent bond formation as synthetic tool, shape-persistent organic cages can be constructed from rather simple molecular building blocks in one step. Here, the yields are usually very high or even quantitatively, because the reversibility of the reaction allows the system to self-correct. Unfortunately, the resulting compounds are more prone to chemical cleavage of the cages than those synthesized by the irreversible approach.
Within this project, we will combine the advantages of both strategies to synthesize chemically and thermally stable nano-sized discrete organic cage compounds in a two-step approach in high yields. To demonstrate the versatility and synthetic power of this approach, pure hydrocarbon cages will be synthesized in a few steps in high yields. Finally, this strategy will make for the first time open and closed-shell fullerenes and heterofullerenes that are isomerically pure, accessible.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Host institution

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG

Address

Seminarstrasse 2
69117 Heidelberg

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 996 000

Beneficiaries (1)

Sort alphabetically

Sort by EU Contribution

Expand all

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG

Germany

EU Contribution

€ 1 996 000

Project information

Grant agreement ID: 725765

Status

Ongoing project

  • Start date

    1 April 2017

  • End date

    31 March 2022

Funded under:

H2020-EU.1.1.

  • Overall budget:

    € 1 996 000

  • EU contribution

    € 1 996 000

Hosted by:

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG

Germany