Objective The enormous amount of diversity that surrounds us raises one of the key questions in evolutionary biology: How do new species originate? Speciation depends on the evolution of reproductive isolation but, with few exceptions, the genes underlying reproductive isolation and their modes of action are unknown. The novelty of this project lies in testing if, in addition to mutations in genes, epigenetics and gene expression are mechanisms that contribute to the process of speciation. For these aims I will use wood ants and their hybrids combining large-scale data sets on genomes, gene expression and genome-wide methylation. These approaches will be complemented with protein modeling of candidate genes resulting in a multidisciplinary project. Further aims are to develop an outreach programme on evolution for high schools and in collaboration with the Finnish Environment Institute to investigate the role of hybrids in forest ecosystems. Together these objectives yield a project that has high scientific standing and societal importance. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological sciencesecologyecosystemsnatural sciencesearth and related environmental sciencesatmospheric sciencesclimatologyclimatic changesnatural sciencesbiological sciencesgeneticsepigeneticsagricultural sciencesagriculture, forestry, and fisheriesforestry Keywords Speciation hybridization evolutionary genetics comparative genomics population genetics Hymenoptera mound-building wood ants science communication Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2016 - Individual Fellowships Call for proposal H2020-MSCA-IF-2016 See other projects for this call Funding Scheme MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF) Coordinator HELSINGIN YLIOPISTO Net EU contribution € 191 325,60 Address YLIOPISTONKATU 3 00014 Helsingin Yliopisto Finland See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 191 325,60