Cel Neurological disorders, particularly dementia, constitute arguably the greatest socioeconomic challenge to the aging European continent. There is growing realization that rodents can serve as models not just for basic neurobiological processes (e.g. synaptic transmission) but also for remarkably complex, primate-like and even human-like cognitive operations such as perception, memory, economics, social interaction, and decision making. Better rodent models for cognition are necessary to test theories on the molecular basis of neurological disorders and to test therapies: only through rodent behavioral neuroscience can the circuits that give rise to cognitive operations be examined and dissected, probed and manipulated. The aim of ERC Advanced Project ‘CONCEPT’ is to understand the neuronal bases of perception, memory and decision making. To achieve this aim, we have developed innovative instrumentation incorporating the following elements: (i) awake rodent interacting with its environment, (ii) precisely controlled sensory stimuli, (iii) imaging of animal’s action, (iv) electrophysiology with moveable microelectrode arrays, (v) optogenetics, (vi) integration and management of all incoming and outgoing signals. Here, we present our plan for bringing these instruments to a stage where they can constitute the initial product line for a spin-off named NeuroMicronica. The community’s interest in NeuroMicronica is already testified by the commercialization of the electrode drive in agreement with a prestigious USA company, by NeuroMicronica’s selection in a technology startup competition, and by the enthusiastic and constructive feedback from collaborators now employing beta versions. The expected outcome of NeuroMicronica will be to make this lab’s longstanding experience in instrumentation available to the community, allowing investigators to better exploit rodent behavioral neuroscience as a model for normal and pathological human cognition. Dziedzina nauki natural sciencesbiological sciencesneurobiologysocial scienceseconomics and businesseconomicsmedical and health sciencesbasic medicineneurologydementia Program(-y) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Temat(-y) ERC-PoC-2016 - ERC-Proof of Concept-2016 Zaproszenie do składania wniosków ERC-2016-PoC Zobacz inne projekty w ramach tego zaproszenia System finansowania ERC-POC - Proof of Concept Grant Instytucja przyjmująca SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE Wkład UE netto € 150 000,00 Adres VIA BONOMEA 265 34136 Trieste Włochy Zobacz na mapie Region Nord-Est Friuli-Venezia Giulia Trieste Rodzaj działalności Higher or Secondary Education Establishments Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Uczestnictwo w unijnych programach w zakresie badań i innowacji Opens in new window sieć współpracy HORIZON Opens in new window Koszt całkowity € 150 000,00 Beneficjenci (1) Sortuj alfabetycznie Sortuj według wkładu UE netto Rozwiń wszystko Zwiń wszystko SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE Włochy Wkład UE netto € 150 000,00 Adres VIA BONOMEA 265 34136 Trieste Zobacz na mapie Region Nord-Est Friuli-Venezia Giulia Trieste Rodzaj działalności Higher or Secondary Education Establishments Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Uczestnictwo w unijnych programach w zakresie badań i innowacji Opens in new window sieć współpracy HORIZON Opens in new window Koszt całkowity € 150 000,00