Objectif A central aim of contemporary research on the origin of species is to identify the genes that are functionally differentiated between nascent species. Understanding the molecular-genetic basis of speciation will answer important questions that are of broad interest to geneticists, ecologists and evolutionary biologists. The RESPEC project will identify such “speciation genes”, map them onto conventional phylogenies and genetically reconstruct the process of speciation. Pollinator-mediated speciation is an attractive system to achieve these goals. Speciation in Petunia is recent, ongoing and prezygotic. Shifts in pollination syndromes are complex but are composed of distinct traits that can be studied individually. The advertising traits color and scent are known to be encoded by major effect genes, but for morphological traits no such information is available.The Objectives of RESPEC are:1. Substitute the four major-effect mutations for advertising traits into the hawkmoth-pollinated species, thereby creating an artificial mimic of the derived bee-pollinated species2. Identify the major-effect genes that specify the morphological differences between a moth- and a hummingbird-pollinated species3. Reconstruct the process of speciation during the shift from hawkmoth to hummingbird pollinationThe identification and functional analysis of a complete set of major-effect genes will for the first time provide comprehensive molecular information about the process of speciation in a single system. This will make it possible to construct a “functional phylogeny” that resolves the conflicts inherent in classical phylogenies of recent radiations. The allele substitution experiments will demonstrate the importance of major-effect genes in speciation as opposed to Darwin’s view of evolution by gradual change. This has never been done before and was long thought to be impossible on theoretical grounds. Champ scientifique natural sciencesbiological sciencesbiological morphologycomparative morphologyengineering and technologymaterials engineeringcolorsnatural sciencesbiological sciencesgeneticsmutationnatural sciencesmathematicspure mathematicsmathematical analysisfunctional analysis Mots‑clés speciation pollination syndromes morphology taxonomy Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Thème(s) ERC-2016-ADG - ERC Advanced Grant Appel à propositions ERC-2016-ADG Voir d’autres projets de cet appel Régime de financement ERC-ADG - Advanced Grant Institution d’accueil UNIVERSITAET BERN Contribution nette de l'UE € 2 499 380,00 Adresse HOCHSCHULSTRASSE 6 3012 Bern Suisse Voir sur la carte Région Schweiz/Suisse/Svizzera Espace Mittelland Bern / Berne Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 2 499 380,00 Bénéficiaires (1) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire UNIVERSITAET BERN Suisse Contribution nette de l'UE € 2 499 380,00 Adresse HOCHSCHULSTRASSE 6 3012 Bern Voir sur la carte Région Schweiz/Suisse/Svizzera Espace Mittelland Bern / Berne Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 2 499 380,00