Objective "The worldwide in vitro diagnostic (IVD) is continually growing. At least 36% of the IVD market comprises point-of-care (POC)tests, which are performed by healthcare professional in various settings or by patients themselves. A large number ofcompanies entered the POC testing market in the recent years while bringing significant technological improvements andnovel concepts to this market. Yet, many important needs for immunodiagnostics are unmet: POC tests still require relativelylarge volumes of samples, cannot readily be multiplexed, are not always accurate, and often involve simple liquiddisplacement ""from point A to point B"" with minimal control over the distribution of reagents and kinetics of reactions.Here, we propose a synergistic project aiming at developing simple-to-use and high-performance microfluidic capillarysystems (""CAPSYS"") for POC testing. Each part of the project will correspond to a complete PhD work with specific skills,methodology, and know-how from the academic and industrial PIs. The common theme for both projects will be the use ofcapillary forces for the autonomous filling of microfluidics by samples and liquids and the integration of reagents andreceptors for analyte detection inside the microfluidic chips. Those microfluidic chips will allow 1-step assays, i.e. assayswherein a non-technical user only needs to load a sample to the chip for performing a biological test.CAPSYS will lead to a new state of the art in terms of POC testing with significant relevance in medicine and diagnostics.CAPSYS will therefore be ideal for early stage researchers (ESRs) in terms of learning various disciplines in depth, creatingnumerous opportunities for publishing, and working on problem-oriented research that can have an impact in the ""realworld""." Fields of science natural sciencesphysical sciencesclassical mechanicsfluid mechanicsmicrofluidics Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Topic(s) MSCA-ITN-2017 - Innovative Training Networks Call for proposal H2020-MSCA-ITN-2017 See other projects for this call Funding Scheme MSCA-ITN-EID - European Industrial Doctorates Coordinator KARLSRUHER INSTITUT FUER TECHNOLOGIE Net EU contribution € 235 371,12 Address KAISERSTRASSE 12 76131 Karlsruhe Germany See on map Region Baden-Württemberg Karlsruhe Karlsruhe, Stadtkreis Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 235 371,12 Participants (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all IBM RESEARCH GMBH Switzerland Net EU contribution € 279 961,58 Address SAEUMERSTRASSE 4 8803 Rueschlikon See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 279 961,58
