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TArgeting Platelet Adhesion receptors in thrombosiS

Objective

TAPAS will position Europe at the forefront of innovative research to prevent thrombosis and thromboinflammation, and will train a uniquely-qualified cohort of ESRs in a highly intersectorial and multi-disciplinary programme that will equip them with the knowledge and transferable skills required in the broad biomedical sector. The research will focus on platelets which are small cells in the blood that play a critical role in prevention of excessive bleeding following injury (haemostasis). Activation of platelets in diseased vessels gives rise to thrombotic disorders such as heart attack and stroke, two of the major causes of morbidity and mortality. Patients at risk of thrombosis are treated with medicines that inhibit platelets for life, but many patients still undergo thrombotic episodes or encounter serious bleeds through diminished haemostasis. There is thus an urgent need for novel and safe anti-platelet medicines that powerfully target thrombosis but preserve haemostasis. In TAPAS, an original and innovative approach will be undertaken to find new ways to target thrombosis through co-operation of academic experts in distinct disciplines with key skills from the private sector. TAPAS will generate and integrate knowledge from analytical complex ‘omics’, advanced microscopy, cell biology, microfluidics, in vivo models, contemporary systems biology and high throughput screens to identify new targets for therapeutic intervention and novel lead compounds or biologics. The research skills developed in this programme are applicable to other complex diseases and represent essential training in modern day research for the next cohort of academic and private sector scientists that are able to convert complex biological understanding into new medicines. The shared knowledge and close interaction between beneficiaries and partners makes this programme ideally suited to an EJD and will deliver 15 ESRs in 21st century biomedical research.

Coordinator

THE UNIVERSITY OF BIRMINGHAM
Net EU contribution
€ 546 575,76
Address
Edgbaston
B15 2TT Birmingham
United Kingdom

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Region
West Midlands (England) West Midlands Birmingham
Activity type
Higher or Secondary Education Establishments
Other funding
€ 546 575,76

Participants (6)

UNIVERSITEIT MAASTRICHT
Netherlands
Net EU contribution
€ 1 021 497,12
Address
Minderbroedersberg 4
6200 MD Maastricht

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Region
Limburg (NL) Zuid-Limburg
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 021 497,12
THE UNIVERSITY OF READING
United Kingdom
Net EU contribution
€ 819 863,64
Address
Whiteknights Campus Whiteknights House
RG6 6AH Reading

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Berkshire
Activity type
Higher or Secondary Education Establishments
Other funding
€ 819 863,64
LEIBNIZ-INSTITUT FUR ANALYTISCHE WISSENSCHAFTEN-ISAS-EV
Germany
Net EU contribution
€ 498 432,96
Address
Bunsen Kirchhoff Strasse 11
44139 Dortmund

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Region
Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt
Activity type
Research Organisations
Other funding
€ 498 432,96
UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT
Germany
Net EU contribution
€ 498 432,96
Address
Josef-schneider-strasse 2
97080 Wurzburg

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Region
Bayern Unterfranken Würzburg, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 498 432,96
ALACRIS THERANOSTICS GMBH
Germany
Net EU contribution
€ 249 216,48
Address
Max Planck Strasse 3
12489 Berlin

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Berlin Berlin Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 249 216,48
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
Spain
Net EU contribution
€ 247 872,96
Address
Colexio De San Xerome Praza Do Obradoiro S/n
15782 Santiago De Compostela

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Region
Galicia A Coruña
Activity type
Higher or Secondary Education Establishments
Other funding
€ 247 872,96

Partners (6)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

Nikon Instruments Europe
Netherlands
Net EU contribution
€ 0,00
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

SEMMELWEIS EGYETEM
Hungary
Net EU contribution
€ 0,00
Address
Ulloi Utca 26
1085 Budapest

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Region
Közép-Magyarország Budapest Budapest
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

SVEUCILISTE U RIJECI
Croatia
Net EU contribution
€ 0,00
Address
Trg Brace Mazuranica 10
51000 Rijeka

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Region
Hrvatska Jadranska Hrvatska Primorsko-goranska županija
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

Intelligent Imaging Innovations GmbH
Germany
Net EU contribution
€ 0,00
Address
Königsallee 9-21
D-37081 Göttingen

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Region
Niedersachsen Braunschweig Göttingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

CELLIX LIMITED
Ireland
Net EU contribution
€ 0,00
Address
Unit 1, Longmile Business Park, Longmile Rd
D12 EK79 Dublin

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

PIVOT PARK SCREENING CENTRE BV
Netherlands
Net EU contribution
€ 0,00
Address
Kloosterstraat 9
5349 AB Oss

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Region
Noord-Brabant Noordoost-Noord-Brabant
Activity type
Research Organisations
Other funding
€ 0,00