Objective
Light interaction with biomaterials is the driving mechanism of fundamental biological processes, from photosynthesis to DNA photodamage, and is a powerful tool in biomedicine for analytical, diagnostic and therapeutic purposes. The main goal of LightDyNAmics is to achieve a complete understanding of the ultrafast dynamical processes at the molecular scale induced by UV light absorption in DNA, and to unveil the mechanisms leading to photodamage of the genetic code. At the same time, our project will transfer this knowledge on light-matter interaction to a broad class of optoelectronic materials, highly relevant for Europe`s high-tech industries.
LightDyNAmics is an academia-industry research environment training 15 Early Stage Researchers (ESRs) by crossing the traditional border between theoretical and experimental expertise. This will be achieved by performing independent, yet interrelated and complementary research projects focussed on photoactivated dynamics of DNA, and by developing a variety of new spectroscopic and computational methods. For all the ESRs, personalised training in advanced techniques will be combined with a broad common interdisciplinary background on dynamical processes in bio-macromolecules.
The consortium brings together 10 leading academic groups with multidisciplinary expertise (chemistry, physics, biology) and a unique blend of experimental and computational skills. 6 innovative companies, from SMEs specialised in click-chemistry and in biosensors to a pharma industry, will be fully integrated in the research and training programme and help promote technological exploitation of its results.
LightDyNAmics will develop innovative molecular probes for DNA/protein interaction, paving the way to new diagnostic tools and new drugs. The understanding of light interaction with organic molecules will impact on basic sciences, from biochemistry to nanosciences, and on industrial applications ranging from healthcare to photonic technologies.
Field of science
- /natural sciences/biological sciences/genetics and heredity/dna
Programme(s)
Call for proposal
H2020-MSCA-ITN-2017
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Funding Scheme
MSCA-ITN-ETN - European Training NetworksCoordinator
00185 Roma
Italy
Participants (12)
75794 Paris
DH1 3LE Durham
1000 Ljubljana
80539 Muenchen
60177 Brno Stred
20133 Milano
4 Dublin
40126 Bologna
1010 Wien
CB2 0AA Cambridge
82061 Neuried
82152 Martinsried
Partners (4)
8008 Zurich
42019 Scandiano
HA5 5NE London
20052 Monza