Resonant Electromagnetic Microscopy: Imaging Cells Electronically

Projektinformationen

REM

ID Finanzhilfevereinbarung: 758769

DOI 10.3030/758769

Abgeschlossenes Projekt

EK-Unterschriftsdatum 22 September 2017

Startdatum 1 Februar 2018

Enddatum 31 Januar 2024

Finanziert unter

• EXCELLENT SCIENCE - European Research Council (ERC)

Gesamtkosten € 1 500 000,00

EU-Beitrag € 1 500 000,00

Koordiniert durch

BILKENT UNIVERSITESI VAKIF
Türkiye

Ziel

Microfluidics technology has been quite successful in fabricating small, low-cost devices with excellent analyte handling capabilities. However, the main detection paradigm in microfluidics has still been optical microscopy — which is a bulky and expensive technique. A chip-scale detection scheme that can provide multidimensional information is much needed for the widespread adoption of lab-on-a-chip technology. So far, successful capacitive and resonant electrical sensors have been deployed in the field; yet the focus of these sensors has been to obtain the electrical volume or location of a particle — which constitutes only a limited piece of information about the analytes. Here we propose to redesign and utilize resonant electrical sensors in a radically different way to obtain images of cells in a microfluidic channel. The technique proposed can also multiplex on-chip cytometry greatly, accomplish low-cost and high-throughput single-cell transit-time characterization, obtain not only the electrical but also the geometrical size of analytes, determine the dielectric permittivity of analytes, in addition to capturing 1D profile or 2D images of cells. At the basic science level, the project will enhance our understanding of the interaction of electromagnetic fields and living matter at the single cell level and may provide new insights on cell motility, growth and mechanics.

Wissenschaftliches Gebiet

• natural sciences › physical sciences › electromagnetism and electronics › electromagnetism
• natural sciences › physical sciences › classical mechanics › fluid mechanics › microfluidics
• engineering and technology › other engineering and technologies › microtechnology › lab on a chip
• natural sciences › physical sciences › optics › microscopy
• engineering and technology › electrical engineering, electronic engineering, information engineering › electronic engineering › sensors

Schlüsselbegriffe

• Lab-on-a-chip

Programm/Programme

• H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme

Thema/Themen

• ERC-2017-STG - ERC Starting Grant

Aufforderung zur Vorschlagseinreichung

ERC-2017-STG

Finanzierungsplan

ERC-STG - Starting Grant

Gastgebende Einrichtung

BILKENT UNIVERSITESI VAKIF

• Netto-EU-Beitrag: € 1 500 000,00
• Adresse: ESKISEHIR YOLU 8 KM ; 06800 Bilkent Ankara ; Türkei
• Region: Batı Anadolu › Ankara › Ankara
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: € 1 500 000,00

Begünstigte (1)

BILKENT UNIVERSITESI VAKIF

Türkei

• Netto-EU-Beitrag: € 1 500 000,00
• Adresse: ESKISEHIR YOLU 8 KM ; 06800 Bilkent Ankara
• Region: Batı Anadolu › Ankara › Ankara
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: € 1 500 000,00