CORDIS
EU research results

CORDIS

English EN
GRACIOUS:  Grouping, Read-Across, CharacterIsation and classificatiOn framework for regUlatory risk assessment of manufactured nanomaterials and Safer design of nano-enabled products

GRACIOUS: Grouping, Read-Across, CharacterIsation and classificatiOn framework for regUlatory risk assessment of manufactured nanomaterials and Safer design of nano-enabled products

Objective

Manufacturing and functionalising materials at the nanoscale leads to a whole array of nanomaterials (NMs) varying in e.g. size, morphology and surface characteristics. Apart from expected benefits, distinctive properties of NMs may also affect (environmental) health risks. Safety assessment requires sufficient information for each NM, but testing every unique NM for their potential adverse effects is virtually impossible. More efficient ways to obtain safety information are needed, which could be achieved by applying grouping and read-across approaches to NMs. On a conceptual level, regulatory accepted approaches for grouping and read-across for NMs already exist, but actual application remains difficult as the required knowledge is not systematically brought together, lacks data curation or is still missing. GRACIOUS will address this urgent need by developing a framework for grouping and read-across based on physicochemical, release, exposure, environmental fate, toxicokinetic and toxicological information. This framework will be delivered as a practical e-tool, fit-for-purpose for various key (regulatory and industrial) stakeholders, who will be engaged from the start of the project. To develop the framework, GRACIOUS will build upon currently available approaches by collating, curating and assimilating existing and new knowledge on intrinsic and extrinsic physicochemical properties in relation to their (environmental) health risk. The resulting framework will support safe innovation by enabling considerations of safety a.o. via grouping and read-across in industrial decision making at various stages of product development. For regulators and policy makers, GRACIOUS will facilitate actual application of grouping and read-across of NMs to enable risk analysis of NMs without extensive testing.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

HERIOT-WATT UNIVERSITY

Address

Riccarton
Eh14 4as Edinburgh

United Kingdom

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 787 325

Participants (23)

Sort alphabetically

Sort by EU Contribution

Expand all

BASF SE

Germany

EU Contribution

€ 669 618,75

GREENDECISION SRL

Italy

EU Contribution

€ 379 375

INSTITUTE OF OCCUPATIONAL MEDICINE

United Kingdom

EU Contribution

€ 327 475

EUROPEAN RESEARCH SERVICES GMBH

Germany

EU Contribution

€ 301 537,50

YORDAS LIMITED

United Kingdom

EU Contribution

€ 249 162,50

DET NATIONALE FORSKNINGSCENTER FORARBEJDSMILJO

Denmark

EU Contribution

€ 411 162,50

BUNDESINSTITUT FUER RISIKOBEWERTUNG

Germany

EU Contribution

€ 466 955

NATURAL ENVIRONMENT RESEARCH COUNCIL

United Kingdom

UNITED KINGDOM RESEARCH AND INNOVATION

United Kingdom

EU Contribution

€ 449 787,50

UNIVERSITAT WIEN

Austria

EU Contribution

€ 309 037,50

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA

Italy

EU Contribution

€ 217 502,50

RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU

Netherlands

EU Contribution

€ 522 787,50

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH

Switzerland

EU Contribution

€ 217 588,75

ACONDICIONAMIENTO TARRASENSE ASSOCIACION

Spain

EU Contribution

€ 383 287,50

AKZO NOBEL PULP AND PERFORMANCE CHEMICALS AB

Sweden

EU Contribution

€ 99 975

IDEACONSULT LIMITED LIABILITY COMPANY

Bulgaria

EU Contribution

€ 205 912,50

JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION

Belgium

EU Contribution

€ 323 947,50

UNILEVER U.K. CENTRAL RESOURCES LIMITED

United Kingdom

EU Contribution

€ 168 568,75

THINKWORKS BV

Netherlands

EU Contribution

€ 210 537,50

Arizona Board of Regents

United States

DUKE UNIVERSITY

United States

ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS

Greece

EU Contribution

€ 124 037,50

EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT

Switzerland

EU Contribution

€ 173 787,50

Project information

Grant agreement ID: 760840

Status

Ongoing project

  • Start date

    1 January 2018

  • End date

    30 June 2021

Funded under:

H2020-EU.2.1.2.2.

  • Overall budget:

    € 7 180 118,75

  • EU contribution

    € 6 999 368,75

Coordinated by:

HERIOT-WATT UNIVERSITY

United Kingdom