NanoSTARS imaging for STEM cell therapy for arthritic joints

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Website (updated throughout the project)

Publications

Characterization of nanosensitive multifractality in submicron scale tissue morphology and its alteration in tumor progression

Auteurs: Nandan Das, Alexandrov Sergey, Katie E. Gilligan, Róisín M. Dwyer, Rolf B. Saager, Nirmalya Ghosh, Martin Leahy
Publié dans: Journal of Biomedical Optics, Numéro 26/01, 2021, ISSN 1083-3668
Éditeur: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.26.1.016003

Segmentation of Knee MRI Data with Convolutional Neural Networks for Semi-Automated Three-Dimensional Surface-Based Analysis of Cartilage Morphology and Composition

Auteurs: Dimitri A. Kessler, James W. MacKay, Stephen M. McDonnell, Robert L. Janiczek, Martin J. Graves, Joshua D. Kaggie, and Fiona J. Gilbert
Publié dans: Osteoarthritis Imaging, Numéro 27726541, 2022, Page(s) 100010, ISSN 2772-6541
Éditeur: Elsevier Ltd
DOI: 10.1016/j.ostima.2022.100010

Platelet Lysate Induces in Human Osteoblasts Resumption of Cell Proliferation and Activation of Pathways Relevant for Revascularization and Regeneration of Damaged Bone

Auteurs: Van Thi Nguyen, Marta Nardini, Alessandra Ruggiu, Ranieri Cancedda, Fiorella Descalzi, Maddalena Mastrogiacomo
Publié dans: International Journal of Molecular Sciences (Int J Mol Sci), Numéro 21 (14), 2020, Page(s) 5123, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21145123

Accessing depth-resolved high spatial frequency content from the optical coherence tomography signal

Auteurs: Sergey Alexandrov, Anand Arangath, Yi Zhou, Mary Murphy, Niamh Duffy, Kai Neuhaus, Georgina Shaw, Ryan McAuley, Martin Leahy
Publié dans: Scientific Reports, Numéro 11/1, 2021, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-96619-7

Magnetic resonance fingerprinting of the pancreas at 1.5 T and 3.0 T

Auteurs: Eva M. Serrao, Dimitri A. Kessler, Bruno Carmo, Lucian Beer, Kevin M. Brindle, Guido Buonincontri, Ferdia A. Gallagher, Fiona J. Gilbert, Edmund Godfrey, Martin J. Graves, Mary A. McLean, Evis Sala, Rolf F. Schulte, Joshua D. Kaggie
Publié dans: Scientific Reports, Numéro 10/1, 2020, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-020-74462-6

Ultra Short Echo Time MRI of Iron-Labelled Mesenchymal Stem Cells in an Ovine Osteochondral Defect Model

Auteurs: Joshua D. Kaggie, Hareklea Markides, Martin J. Graves, James MacKay, Gavin Houston, Alicia El Haj, Fiona Gilbert, Frances Henson
Publié dans: Scientific Reports, Numéro 10/1, 2020, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-020-64423-4

Simple Characterization Scheme for Optical Coherence Tomography Systems With Application to a Commercial and a Near-Isometric Resolution Fibre-Based System

Auteurs: Rajib Dey; Yi Zhou; Kai Neuhaus; Sergey Alexandrov; Andrew Nolan; Ting-Chiao Chang; Martin Leahy
Publié dans: IEEE Photonics Journal, Numéro 14, 1, 2022, ISSN 1943-0655
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.1109/jphot.2021.3135058

Effectively Measuring Exercise‐Related Variations in T1ρ and T2 Relaxation Times of Healthy Articular Cartilage

Auteurs: Dimitri A. Kessler, James W. MacKay, Scott McDonald, Stephen McDonnell, Andrew J. Grainger, Alexandra R. Roberts, Robert L. Janiczek, Martin J. Graves, Joshua D. Kaggie, Fiona J. Gilbert
Publié dans: Journal of Magnetic Resonance Imaging, Numéro 52/6, 2020, Page(s) 1753-1764, ISSN 1053-1807
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jmri.27278

Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization

Auteurs: Sergey Alexandrov, Paul M. McNamara, Nandan Das, Yi Zhou, Gillian Lynch, Josh Hogan, Martin Leahy
Publié dans: Applied Physics Letters, Numéro 115/12, 2019, Page(s) 121105, ISSN 0003-6951
Éditeur: American Institute of Physics
DOI: 10.1063/1.5110459

The use of large animals to facilitate the process of MSC going from laboratory to patient—‘bench to bedside’

Auteurs: W. E. Hotham, F. M. D. Henson
Publié dans: Cell Biology and Toxicology, Numéro 36/2, 2020, Page(s) 103-114, ISSN 0742-2091
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10565-020-09521-9

Progenitor Cells Activated by Platelet Lysate in Human Articular Cartilage as a Tool for Future Cartilage Engineering and Reparative Strategies

Auteurs: Simonetta Carluccio, Daniela Martinelli, Maria Elisabetta Federica Palamà, Rui Cruz Pereira, Roberto Benelli, Ana Guijarro, Ranieri Cancedda, Chiara Gentili
Publié dans: Cells, Numéro 9/4, 2020, Page(s) 1052, ISSN 2073-4409
Éditeur: MDPI AG
DOI: 10.3390/cells9041052

Noninvasive detection of nanoscale structural changes in cornea associated with cross‐linking treatment

Auteurs: Yi Zhou, Sergey Alexandrov, Andrew Nolan, Nandan Das, Rajib Dey, Martin Leahy
Publié dans: Journal of Biophotonics, Numéro 13/6, 2020, ISSN 1864-063X
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.201960234

Nanosensitive optical coherence tomography to assess wound healing within the cornea

Auteurs: Cerine Lal, Sergey Alexandrov, Sweta Rani, Yi Zhou, Thomas Ritter, Martin Leahy
Publié dans: Biomedical Optics Express, Numéro 11/7, 2020, Page(s) 3407, ISSN 2156-7085
Éditeur: The Optical Society
DOI: 10.1364/boe.389342

Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography

Auteurs: Nandan Das, Alexandrov Sergey, Yi Zhou, Katie E. Gilligan, Róisín M. Dwyer, Martin Leahy
Publié dans: Nanoscale Advances, Numéro 2/7, 2020, Page(s) 2853-2858, ISSN 2516-0230
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d0na00371a

The optimisation of deep neural networks for segmenting multiple knee joint tissues from MRIs

Auteurs: Dimitri A. Kessler, James W. MacKay, Victoria A. Crowe, Frances M.D. Henson, Martin J. Graves, Fiona J. Gilbert, Joshua D. Kaggie
Publié dans: Computerized Medical Imaging and Graphics, Numéro 86, 2020, Page(s) 101793, ISSN 0895-6111
Éditeur: Elsevier BV
DOI: 10.1016/j.compmedimag.2020.101793

Evaluation of signal degradation due to birefringence in a multiple reference optical coherence tomography system with polarization-based balanced detection

Auteurs: Anand Arangath; Kai Neuhaus; Sergey Alexandrov; Martin Leahy
Publié dans: IEEE Photonics Journal, Numéro 14 (4), 2022, Page(s) 1-13, ISSN 1943-0655
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.1109/jphot.2022.3189809

Contrast agents for photoacoustic imaging: a review of stem cell tracking.

Auteurs: Soorya James; Kai Neuhaus; Mary Murphy; Martin J. Leahy; Martin J. Leahy
Publié dans: Stem Cell Research & Therapy, Numéro 12, 2021, Page(s) 511, ISSN 1757-6512
Éditeur: BioMed Central
DOI: 10.1186/s13287-021-02576-3

Spatial and Spectral Mapping and Decomposition of Neural Dynamics and Organization of the Mouse Brain with Multispectral Optoacoustic Tomography.

Auteurs: Ivan Olefir; Ara Ghazaryan; Hong Yang; Jaber Malekzadeh-Najafabadi; Sarah Glasl; Panagiotis Symvoulidis; Valerie B. O’Leary; George Sergiadis; Vasilis Ntziachristos; Saak V. Ovsepian
Publié dans: Cell Reports, Numéro 26, 10, 2019, Page(s) 2833-2846.e3, ISSN 2211-1247
Éditeur: Cell Press
DOI: 10.1016/j.celrep.2019.02.020

Label Free Ultra-Sensitive Imaging with Sub-Diffraction Spatial Resolution

Auteurs: Sergey Alexandrov, Nandan Das, James McGrath, Peter Owens, Colin J. R. Sheppard, Francesca Boccafoschi, Cinzia Giannini, Teresa Sibillano, Hrebesh Subhash, Martin Leahy
Publié dans: 2019 21st International Conference on Transparent Optical Networks (ICTON), 2019, Page(s) 1-4, ISBN 978-1-7281-2779-8
Éditeur: IEEE
DOI: 10.1109/icton.2019.8840220

Ultra-sensitive label free imaging below the resolution limit (Conference Presentation)

Auteurs: Sergey A. Alexandrov, James McGrath, Colin Sheppard, Francesca Boccafoschi, Cinzia Giannini, Teresa Sibillano, Hrebesh Subhash, Josh Hogan, Martin Leahy
Publié dans: Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVI, 2019, Page(s) 4, ISBN 9781-510624252
Éditeur: SPIE
DOI: 10.1117/12.2502479

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