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Developing Multipurpose Nicotiana Crops for Molecular Farming using New Plant Breeding Techniques

Objective

A group of New Plant Breeding Techniques (NPBT) has opened unprecedented opportunities in agriculture. Those NPBTs are at least as efficient and often more precise than previous traditional and GM techniques, while circumventing the introduction of heritable transgenes from distant species in the plant genome. Properly communicated, NPBTs are expected to gain wide acceptance, especially when applied to breeding objectives which are seen as beneficial for the society. A well-perceived objective is Molecular Farming, which refers to the use of plants for the production of valuable biomolecules (e. g. biopharmaceuticals). Cultivated tobacco (Nicotiana tabacum) and its close Australian relative Nicotiana benthamiana, are preferred species in Molecular Farming due to their favourable features: non-food crops, easy tissue regeneration, high productivity, rich secondary metabolism and availability of genetic tools. In sharp contrast, traditional tobacco cultivation is in serious decline in the EU, causing serious social problems in many rural areas. NEWCOTIANA aims to revitalize those areas by breeding efficient Nicotiana biofactories of high-value non-smoking products as alternatives for traditional tobacco crops. NEWCOTIANA will develop the most advanced tobacco NPBTs toolbox, easily transferable to other plants. This will position EU in the avant-garde of breeding innovation. This toolbox will be used to create elite multipurpose Nicotiana varieties improved in product-specific traits (bioproduct quality, stability and yield), next to more general traits as biomass, resilience and biosafety. The “Newcotiana” varieties will be carefully tested in relevant pre-industrial environments for the production of end-value chemicals, namely proteins and metabolites for health and nutriceutical use. Ethical, social and legal aspects will be closely monitored and public and stakeholder engagement will be assured using innovative science communication methodologies.

Call for proposal

H2020-NMBP-BIO-2017
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Funding Scheme

RIA - Research and Innovation action

Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Address
Calle Serrano 117
28006 Madrid
Spain
Activity type
Research Organisations
EU contribution
€ 702 581,25

Participants (18)

ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE
United Kingdom
EU contribution
€ 459 862,50
Address
Egham Hill University Of London
TW20 0EX Egham
Activity type
Higher or Secondary Education Establishments
AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE
Italy
EU contribution
€ 465 000
Address
Lungotevere Grande Ammiraglio Thaon Di Revel 76
000196 Roma
Activity type
Research Organisations
VIB VZW
Belgium
EU contribution
€ 359 475
Address
Rijvisschestraat 120
9052 Zwijnaarde - Gent
Activity type
Research Organisations
ASOCIACION EMPRESARIAL DE INVESTIGACION CENTRO TECNOLOGICO NACIONAL AGROALIMENTARIO EXTREMADURA
Spain
EU contribution
€ 292 107,50
Address
Ctra Villafranco A Balboa Km 1,2
06195 Villafranco Del Guadiana (Badajoz)
Activity type
Research Organisations
UNIVERSITAET FUER BODENKULTUR WIEN
Austria
EU contribution
€ 426 131,25
Address
Gregor Mendel Strasse 33
1180 Wien
Activity type
Higher or Secondary Education Establishments
JOHN INNES CENTRE
United Kingdom
EU contribution
€ 349 792,50
Address
Norwich Research Park Colney
NR4 7UH Norwich
Activity type
Research Organisations
KARLSRUHER INSTITUT FUER TECHNOLOGIE
Germany
EU contribution
€ 388 271,25
Address
Kaiserstrasse 12
76131 Karlsruhe
Activity type
Higher or Secondary Education Establishments
LEIBNIZ-INSTITUT FUR PFLANZENBIOCHEMIE
Germany
EU contribution
€ 251 250
Address
Weinberg 3
06120 Halle
Activity type
Research Organisations
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
EU contribution
€ 576 125
Address
Hofgartenstrasse 8
80539 Muenchen
Activity type
Research Organisations
BIOFACTION KG
Austria
EU contribution
€ 338 131,25
Address
Kundmanngasse 39/12
1030 Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 371 321,25
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 495 513,75
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations
Philip Morris Products S.A.
Switzerland
EU contribution
€ 306 250
Address
Quai Jeanrenaud 56
2000 Neuchatel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ST GEORGE'S HOSPITAL MEDICAL SCHOOL
United Kingdom
EU contribution
€ 562 822,50
Address
Cranmer Terrace
SW17 0RE London
Activity type
Higher or Secondary Education Establishments
IDOASIS 2002 SL
Spain
EU contribution
€ 343 875
Address
C/ Tellez, 25 2-1
28007 Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
QUEENSLAND UNIVERSITY OF TECHNOLOGY - QLD QUT
Australia
EU contribution
€ 0
Address
George Street 2
4001 Brisbane
Activity type
Higher or Secondary Education Establishments
SESDERMA SL
Spain
EU contribution
€ 191 987,50
Address
Calle Massamagrell 5 Poligono Industrial Rafelbunyol
46138 Rafelbunyol
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NEUTRAL SUPPLY CHAIN LIMITED
United Kingdom
EU contribution
€ 319 062,50
Address
337 Bath Road
SL1 5PR Slough, Berkshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)