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Pilot line for paper based electrochemical test strips dedicated to quantitative biosensing in liquids

Pilot line for paper based electrochemical test strips dedicated to quantitative biosensing in liquids

Objective

IMPETUS will combine paper, printing and microchip technologies to realise a pilot line capable of manufacturing fully integrated paper-based electrochemical biosensors that directly transfer the measured data to the user’s smartphone. These biosensors will be designed as self-powered disposable test strips that combine the simplicity of lateral flow tests with quantitative readout, which is enabled by the implemented electrochemical detection method. As an application example, we will fulfil the consumer need for fast point-of-care discrimination between bacterial and viral infections.
In particular, IMPETUS will combine screen-, flexo- and inkjet-printing in a seamless roll-to-roll pilot line compatible to high-throughput fabrication. Here, the paper is employed as substrate for the printed circuits and a microchip, but also as active component of the printed battery as well as of the biosensor. This we will achieve by developing new technologies for paper manufacturing, coating and surface modification, and the respective processing will work hand in hand with the ink development (cellulose-based inks for fabricating the printed battery as well as bio-inks for surface functionalization and reagent deposition). A highly integrated and energy-efficient silicon microchip will be developed that enables electrochemical data acquisition, storage and contactless NFC transmission, and the microchip will be mounted onto the paper substrate by an inline placement process.
In summary, the IMPETUS pilot line will pave the way towards the real world application of paper-based quantitative electrochemical diagnostic test strips, thereby clearly advancing the current state-of-the-art, which up to now has mostly focussed on individual fabrication processes and device concepts. The IMPETUS pilot line is conceived in such a way that during the project, all printing and assembly processes will be implemented and validated.
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Coordinator

AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH

Address

Giefinggasse 4
1210 Wien

Austria

Activity type

Research Organisations

EU Contribution

€ 1 122 628

Participants (14)

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DPI HOLDING GMBH

Austria

EU Contribution

€ 491 015

INFINEON TECHNOLOGIES AUSTRIA AG

Austria

EU Contribution

€ 703 828

MAURER SERVICES GMBH

Germany

EU Contribution

€ 692 380

MELECS EWS GMBH

Austria

EU Contribution

€ 287 719

PAPIERTECHNISCHE STIFTUNG

Germany

EU Contribution

€ 469 631

R-BIOPHARM AG

Germany

EU Contribution

€ 290 565

RICOH UK PRODUCTS LIMITED

United Kingdom

EU Contribution

€ 652 342

SARALON

Germany

EU Contribution

€ 301 950

SCHOELLER TECHNOCELL GMBH & CO KG

Germany

EU Contribution

€ 16 405,29

GWENT ELECTRONIC MATERIALS LIMITED

United Kingdom

EU Contribution

€ 129 938

TECHNISCHE UNIVERSITAET CHEMNITZ

Germany

EU Contribution

€ 692 542

PRO-ACTIVE

Belgium

EU Contribution

€ 63 963

MAURER ENGINEERING UG (HAFTUNGSBESCHRANKT)

Germany

EU Contribution

€ 191 523

FELIX SCHOELLER HOLDING GMBH & CO KG

Germany

EU Contribution

€ 289 875,71

Project information

Grant agreement ID: 761167

Status

Ongoing project

  • Start date

    1 January 2018

  • End date

    31 December 2021

Funded under:

H2020-EU.2.1.2.

  • Overall budget:

    € 6 396 305

  • EU contribution

    € 6 396 305

Coordinated by:

AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH

Austria