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Preservation of microorganisms by understanding the protective mechanisms of oligosaccharides

Preservation of microorganisms by understanding the protective mechanisms of oligosaccharides

Objective

Microorganisms offer a large variety of functionalities that remains under-exploited due to the current inability to perform long term preservation at an industrial scale. PREMIUM project is a four-year multidisciplinary project involving a consortium of 5 academic partners from 5 European countries (France, Spain and Portugal) and 1 from third country (Argentina) and 3 industrial partners (France, United Kingdom and Spain). The project aims at developing new strategies to preserve lactic acid bacteria from laboratory to industrial scale. The innovative approaches of the project lay on: i) producing oligosaccharides of original composition for protecting cells; ii) developing novel preservation process based on encapsulation and evaluating the environmental impact of the whole system of production and stabilization of micro-organisms from the laboratory step iii) developing high-throughput characterization and screening tools such as vibrational spectroscopy. A multicriteria analysis approach will be developed to identify the most promising strategies for industrial eco-friendly preservation of micro-organisms.
PREMIUM project involves 8 Workpackages (WP): WP1 is dedicated to project coordination and management. WP2 focuses on the production and characterization of a wide range of oligosaccharides. WP3 investigates and optimises new process technologies for preserving lactic acid bacteria. WP4 studies the mechanisms of bacteria preservation by oligosaccharides for defining the relevant composition and structure of oligosaccharides. WP5 focus on the scale up of processes, application to other cells and transfer of technologies to industry. The other WPs are dedicated to communication, networking and outreach activities (WP6), dissemination and exploitation of the results (WP7), ethics requirements (WP8).
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Coordinator

INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

Address

Rue De L'Universite 147
75338 Paris Cedex 07

France

Activity type

Research Organisations

EU Contribution

€ 130 500

Participants (7)

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ASYMPTOTE LIMITED

United Kingdom

EU Contribution

€ 63 000

UNIVERSIDADE DE COIMBRA

Portugal

EU Contribution

€ 72 000

FUNDACIO INSTITUT DE CIENCIES FOTONIQUES

Spain

EU Contribution

€ 58 500

Universidade da Madeira

Portugal

EU Contribution

€ 67 500

BIOSEARCH S.A.

Spain

EU Contribution

€ 121 500

INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT - AGRO PARIS TECH

France

EU Contribution

€ 121 500

CLOCK-T

France

Partners (1)

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CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)

Project information

Grant agreement ID: 777657

Status

Ongoing project

  • Start date

    1 January 2018

  • End date

    31 December 2021

Funded under:

H2020-EU.1.3.3.

  • Overall budget:

    € 634 500

  • EU contribution

    € 634 500

Coordinated by:

INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

France