Skip to main content

Mid-infrared arthroscopy innovative imaging system for real-time clinical in depth examination and diagnosis of degenerative joint diseases

Objective

MIRACLE will take towards commercialization the first mid-infrared (MIR) arthroscopy probe for in-depth evaluation of articular cartilage enabling early diagnosis of degenerative joint diseases such as osteoarthritis (OA). The proposed device is intended for use during a minimally invasive surgery (arthroscopy). Currently, the surgeon’s decision-making is based on visual inspection and manual probing of the cartilage tissue which is highly subjective and of poor repeatability. Untreated or not-correctly treated joint injury will most likely progress towards OA, which will lead to joint pain, movement limitation, joint failure, and ultimately disability and joint replacement. OA constitutes a major challenge for the health systems and affects 242 million people globally. Moreover, OA is highly prevalent in Europe with an estimated 19.7-42.3% in the elderly population. MIRACLE concept is to access the biochemical on articular cartilage, which precedes OA. The feasibility of this approach as a diagnostic method has been demonstrated by MIRACLE consortium (TRL4). MIRACLE has also prototyped a MIR-probe with potential use for diagnostics (TRL4). By technology development reaching TRL 6-7, MIRACLE will bring to the arthroscopy market the first MIR-based probe providing an unique, accurate and quantitative diagnostic tool for the orthopedic surgeon. This will be achieved combining three novel photonics components: (i) a quantum cascade laser array tailored to biodiagnostics, (ii) an on-chip beam combiner for efficient radiation coupling, and (iii) MIR sensing probe for imaging. These components will be integrated in a medical device to be placed in the arthroscopy market (valued at $4 billion in 2015). In addition to add value to the European medical equipment industry, MIRACLE strives towards cost reduction of OA patients (currently costs/patient/year €10,452) contributing to more affordable public health care and promoting wellbeing in the European ageing population.

Call for proposal

H2020-ICT-2017-1
See other projects for this call

Funding Scheme

IA - Innovation action

Coordinator

OULUN YLIOPISTO
Address
Pentti Kaiteran Katu 1
90014 Oulu
Finland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 146 325

Participants (13)

UNIVERSITAET ULM
Germany
EU contribution
€ 842 500
Address
Helmholtzstrasse 16
89081 Ulm
Activity type
Higher or Secondary Education Establishments
ITA-SUOMEN YLIOPISTO
Finland
EU contribution
€ 585 856,25
Address
Yliopistonranta 1 E
70211 Kuopio
Activity type
Higher or Secondary Education Establishments
NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET
Norway
EU contribution
€ 538 431,25
Address
Universitetstunet 3
1433 As
Activity type
Higher or Secondary Education Establishments
POHJOIS-SAVON SAIRAANHOITOPIIRIN KUNTAYHTYMA
Finland
EU contribution
€ 173 750
Address
Pl 100
70029 Kys
Activity type
Research Organisations
UNIVERSITEIT UTRECHT
Netherlands
EU contribution
€ 293 376,25
Address
Heidelberglaan 8
3584 CS Utrecht
Activity type
Higher or Secondary Education Establishments
NANOPLUS NANOSYSTEMS AND TECHNOLOGIES GMBH
Germany
EU contribution
€ 797 204,63
Address
Oberer Kirschberg 4
97218 Gerbrunn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
OPTOPRECISION GMBH
Germany
EU contribution
€ 470 312,50
Address
Auf Der Hoehe 15
28357 Bremen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
IRIS TECHNOLOGY SOLUTIONS, SOCIEDAD LIMITADA
Spain
EU contribution
€ 352 450
Address
Calle Velazquez, No 94 Primera Planta
28006 Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ART PHOTONICS
Germany
EU contribution
€ 310 187,50
Address
Rudower Chaussee 46
12489 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INEB-INSTITUTO NACIONAL DE ENGENHARIA BIOMEDICA
Portugal
EU contribution
€ 361 530
Address
Rua Alfredo Allen 208
4200 135 Porto
Activity type
Research Organisations
ASOCIACION ESPANOLA DE NORMALIZACION
Spain
EU contribution
€ 77 500
Address
Calle Genova 6
28004 Madrid
Activity type
Other
PHOTONICS FINLAND
Finland
EU contribution
€ 106 367,50
Address
Länsikatu 15
80110 Joensuu
Activity type
Other
UNIVERSIDADE CATOLICA PORTUGUESA
Portugal
EU contribution
€ 77 845
Address
Palma De Cima
1649 023 Lisboa
Activity type
Higher or Secondary Education Establishments