CORDIS
EU research results

CORDIS

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Point-of-care molecular diagnostics of psoriasis and eczema – peLabDisk

Project information

Grant agreement ID: 786445

  • Start date

    1 March 2018

  • End date

    31 August 2019

Funded under:

H2020-EU.1.1.

  • Overall budget:

    € 150 000

  • EU contribution

    € 150 000

Hosted by:

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN

Germany

Objective

Innovative and effective biological therapies exist to treat non-communicable inflammatory skin diseases (ncISD). However, diagnostic guidance when and how to use them is imprecise; no substantial innovation was made for decades. Due to this lack of innovation, high socio-economic costs are caused by ineffective unguided treatment – a waste of resources. Existing ERC research aims at establishing individualised medicine in ncISD (IMCIS, grant agreement 676858). First success is a biomarker to distinguish psoriasis from eczema. Due to disease heterogeneity, these two ncISD cannot be distinguished in 10% of all cases with current gold standard diagnostics. Treating patients with the wrong therapy as a consequence of mis-diagnosis is inefficient and might even be harmful. This PoC proposal follows the path of IMCIS and closes the gap between ERC research and a prototype device of a point-of-care microfluidic testing device to distinguish psoriasis and eczema based on their molecular signature (peLabDisk). The proposal is feasible, as there is a high level of expertise created by joint forces of researchers of the Technical University of Munich and Hahn-Schickard providing extensive competence in the development, construction and manufacturing of microfluidic cartridges for medical applications. The project plan consists of well-defined work packages and milestones. Furthermore, success of the individual work packages is supervised by experienced experts (TUM Entrepeneurship). This PoC proposal is not the end – there is a clear roadmap and a detailed strategy for the post-PoC phase including potential end-user network and supported foundation of a spin-off company. peLabDisk represents the first approach of molecular diagnostics in the field that is easy-to-handle, robust and valid, as well as economic. It is superior to current gold standard diagnostics. Furthermore, peLabDisk is a use-case for point-of-care molecular diagnostics in complex inflammatory diseases.

Host institution

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN

Address

Ismaninger Strasse 22
81675 Muenchen

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 150 000

Beneficiaries (1)

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN

Germany

EU Contribution

€ 150 000

Project information

Grant agreement ID: 786445

  • Start date

    1 March 2018

  • End date

    31 August 2019

Funded under:

H2020-EU.1.1.

  • Overall budget:

    € 150 000

  • EU contribution

    € 150 000

Hosted by:

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN

Germany