Deciphering molecular pathways of circadian clock communication

Pubblicazioni

Beyond circadian rhythms: emerging roles of ultradian rhythms in control of liver functions

Autori: Gad Asher* and Bokai Zhu.
Pubblicato in: Hepatology, Numero 77(3), 2023, Pagina/e 1022-1035
Editore: AASLD
DOI: 10.1002/hep.32580

Circadian clocks' interactions with oxygen sensing and signalling

Autori: Yaarit Adamovich, Vaishnavi Dandavate, Gad Asher
Pubblicato in: ACTA Physioloigca, Numero 234 (2), 2022
Editore: Wiley
DOI: 10.1111/apha.13770

Circadian regulation of liver function: from molecular mechanisms to disease pathophysiology

Autori: Nityanand Bolshette, Hussam Ibrahim, Hans Reinke, Gad Asher
Pubblicato in: Nat Rev Gastroenterol Hepatol, 2023
Editore: Nature
DOI: 10.1038/s41575-023-00792-1

Input integration by the circadian clock exhibits nonadditivity and fold-change detection

Autori: Gal Manella; Nityanand Bolshette; Marina Golik; Gad Asher
Pubblicato in: Proceedings of the National Academy of Sciences - PNAS, Numero 1, 2022, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2209933119

The liver-clock coordinates rhythmicity of peripheral tissues in response to feeding

Autori: Gal Manella, Elizabeth Sabath, Rona Aviram, Vaishnavi Dandavate, Saar Ezagouri, Marina Golik, Yaarit Adamovich and Gad Asher
Pubblicato in: Nature metabolism, 2021, ISSN 2522-5812
Editore: Berlin : Springer Nature
DOI: 10.1038/s42255-021-00395-7

Ultradian rhythms of AKT phosphorylation and gene expression emerge in the absence of the circadian clock components Per1 and Per2

Autori: Rona Aviram; Vaishnavi Dandavate; Gal Manella; Marina Golik; Gad Asher
Pubblicato in: PLoS Biology, Numero 3, 2021, ISSN 1544-9173
Editore: Public Library of Science
DOI: 10.1371/journal.pbio.3001492

The human blood transcriptome exhibits time-of-day dependent response to hypoxia – lessons from the highest city in the world

Autori: Gal Manella, Saar Ezagouri, Benoit Champigneulle, Jonathan Gaucher, Monique Mendelson, Emeline Lemarie, Emeric Stauffer, Aurélien Pichon, Connor A. Howe, Stéphane Doutreleau, Marina Golik, Samuel Verges and Gad Asher
Pubblicato in: Cell reports, 2022, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2022.111213

Hypoxia induces a time- and tissue-specific response that elicits intertissue circadian clock misalignment

Autori: Gal Manella, Rona Aviram, Nityanand Bolshette, Sapir Muvkadi, Marina Golik, David F. Smith, Gad Asher
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 117/1, 2020, Pagina/e 779-786, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1914112117

Clock proteins and training modify exercise capacity in a daytime-dependent manner

Autori: Yaarit Adamovich, Vaishnavi Dandavate, Saar Ezagouri, Gal Manella, Ziv Zwighaft, Jonathan Sobel, Yael Kuperman, Marina Golik, Asher Auerbach, Maxim Itkin, Sergey Malitsky and Gad Asher
Pubblicato in: Proceedings of the National Academy of Sciences - PNAS, 2021, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2101115118

Snapshot: The liver by day and by night

Autori: Rona Aviram, Gal Manella and Gad Asher
Pubblicato in: Journal of Hepatology, 2021, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/j.jhep.2021.01.011

Physiological and Molecular Dissection of Daily Variance in Exercise Capacity

Autori: Saar Ezagouri, Ziv Zwighaft, Jonathan Sobel, Sébastien Baillieul, Stéphane Doutreleau, Benjamin Ladeuix, Marina Golik, Samuel Verges, Gad Asher
Pubblicato in: Cell Metabolism, Numero 30/1, 2019, Pagina/e 78-91.e4, ISSN 1550-4131
Editore: Cell Press
DOI: 10.1016/j.cmet.2019.03.012

Oxygen and Carbon Dioxide Rhythms Are Circadian Clock Controlled and Differentially Directed by Behavioral Signals

Autori: Yaarit Adamovich, Benjamin Ladeuix, Jonathan Sobel, Gal Manella, Adi Neufeld-Cohen, Mohammad H. Assadi, Marina Golik, Yael Kuperman, Ariel Tarasiuk, Maarten P. Koeners, Gad Asher
Pubblicato in: Cell Metabolism, Numero 29/5, 2019, Pagina/e 1092-1103.e3, ISSN 1550-4131
Editore: Cell Press
DOI: 10.1016/j.cmet.2019.01.007

Circa-SCOPE: high-throughput, live single-cell imaging method for analysis of circadian clock resetting

Autori: Gal Manella, Dan Aizik, Rona Aviram, Marina Golik and Gad Asher
Pubblicato in: Nature Communications, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-26210-1

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