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Re-Mapping the Numerical Brain.

Objective

Little is known on how the math system overcomes selective damage to parts of its brain bases. Indeed, brain adaptation has been observed in other domains, such as language: the loss of key language-related areas very often leads to brain reconfiguration for an ultimate successful behavior. Functional redundancies and remapping become visible in brain tumor patients for whom the slow growth of a tumor allows for functional reorganization. Re-MAPMATH aims the tracking of plastic brain changes behind math functions before and after surgery in brain tumor patients. For this, we will use neuroimaging techniques that allow for an optimal spatiotemporal resolution, entailing an advanced approach in the field of math cognition. The project main objectives are: (1) to precisely describe the brain bases for different math processes in the normal population, including functional activations and functional connectivity (2) to track how these default activations, functional and structural connectivity are modified by the growth of a tumor and (3) by the resection of the tumor, measuring three months after surgery. Finally (4), we aim the detection of commonalities across patients with the goal of describing redundancies and alternative pathways that allow a successful numerical behavior. In turn, uncovering these alternative neurofunctional systems can ultimately explain compensation in math disorders, as well as provide with useful information for the rehabilitation of essential math functions after surgery.
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Coordinator

UNIVERSITA DEGLI STUDI DI PADOVA

Address

Via 8 Febbraio 2
35122 Padova

Italy

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 168 277,20

Project information

Grant agreement ID: 793071

Status

Ongoing project

  • Start date

    1 June 2018

  • End date

    31 May 2020

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 168 277,20

  • EU contribution

    € 168 277,20

Coordinated by:

UNIVERSITA DEGLI STUDI DI PADOVA

Italy