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Epigenetics and System Biology of Stem cells and Reprogramming

Objective

Chromatin is the basic regulatory unit of life, and as such it controls developmental and functional states of all cells, including pluripotency. In recent years methods to study chromatin and transcription have dramatically improved and expanded to genome-wide global approaches on the one hand, and single cell biology on the other, allowing systems-level understanding of epigenetic regulation of stem cells, reprogramming and development.
The Epigenetics and Systems Biology of Stem Cells and Reprogramming Network (EpiSyStem) is comprised of 8 world renowned, ERC-granted researchers, 2 professional leading industrial partners and supported by 3 partner organizations and 3 international world acclaimed scientists as an advisory board, to provide a unique training environment. EpiSyStem combines chromatin biology in stem cells, early embryos and reprogramming, including the modelling of human neurological, chromatin-related diseases with bioinformatics, epigenetics/epigenomics, and systems biology at the population and single cell / single embryo level. This multidisciplinary approach will enable profound training and deep, systems-level understanding of chromatin biology and epigenetic regulation of stem cells, differentiation and reprogramming, with a strong support by industrial partners.
The objectives of EpiSyStem is to create a European mesh in which 14 outstanding PhD students will be trained in fundamental questions of biological research, be exposed to the latest technologies and breakthroughs, supervised by leading experts with international contacts - with the aim to facilitate their path to future leadership with holistic view, coupled with the forefront of the current epigenetic research in the field. They will enjoy exchange programs, workshops on emerging topics in stem cell epigenetics and bioinformatics, international conferences and meetings, and will communicate their findings to the scientific community as well as the general public.

Field of science

  • /medical and health sciences/medical biotechnology/cells technologies/stem cells
  • /natural sciences/biological sciences/cell biology
  • /natural sciences/biological sciences/genetics and heredity/epigenetics
  • /medical and health sciences/clinical medicine/embryology

Call for proposal

H2020-MSCA-ITN-2017
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

THE HEBREW UNIVERSITY OF JERUSALEM
Address
Edmond J Safra Campus Givat Ram
91904 Jerusalem
Israel
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 780 901,56

Participants (7)

INSTITUT CURIE
France
EU contribution
€ 525 751,20
Address
Rue D'ulm 26
75231 Paris
Activity type
Research Organisations
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany
EU contribution
€ 498 432,96
Address
Ingolstadter Landstrasse 1
85764 Neuherberg
Activity type
Research Organisations
UNIVERSITA DEGLI STUDI DI MILANO
Italy
EU contribution
€ 516 122,64
Address
Via Festa Del Perdono 7
20122 Milano
Activity type
Higher or Secondary Education Establishments
STICHTING KATHOLIEKE UNIVERSITEIT
Netherlands
EU contribution
€ 255 374,28
Address
Geert Grooteplein Noord 9
6525 EZ Nijmegen
Activity type
Higher or Secondary Education Establishments
KADIMASTEM LTD

Participation ended

Israel
EU contribution
€ 260 300,52
Address
Pinchas Sapir Str 7 Weizmann Science Park
74140 Nes Ziona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
Netherlands
EU contribution
€ 510 748,56
Address
Kloveniersburgwal 29 Het Trippenhuis
1011 JV Amsterdam
Activity type
Other
DIAGENODE
Belgium
EU contribution
€ 250 560
Address
Rue Du Bois Saint Jean 3 Liege Park Science
4102 Seraing
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)