CORDIS
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Cell-free Ti-based Medical Implants due to Laser-induced Microstructures

Project information

Grant agreement ID: 800832

  • Start date

    1 July 2018

  • End date

    31 December 2019

Funded under:

H2020-EU.1.2.1.

  • Overall budget:

    € 100 000

  • EU contribution

    € 100 000

Coordinated by:

UNIVERSITAT LINZ

Austria

Objective

New miniaturized and smart medical implants are more and more used in all medical fields, including miniaturized pacemakers. These implants with a casing consisting often of a Ti-alloy may have to be removed after some months or several years and shall therefore not be completely overgrown by the cells. In the framework of the ongoing FET Open project LiNaBioFluid, we successfully demonstrated that self-organized sharp cones or spikes at Ti-alloy substrates created by pulsed laser-ablation can result not only in complete wetting by water and body fluids but at the same time provide too little surface for the cells (i.e., fibroblasts) to grow on. Compared to flat surfaces, the cell density on the microstructures is significantly lowered, the coverage is incomplete and the cells have a clearly different morphology. The best results regarding suppression of cell growth are obtained on structures created by femtosecond Ti:sapphire laser irradiation, which are subsequently electrochemically treated. The goal of the Coordination and Support Action CellFreeImplant is to find strategic partners (end-users) for future development of smart medical implants addressing wide-spread patients needs for instance in the field of cardio-vascular diseases. The project activities include the identification of the market segments and needs and assessment of the technology with end-users.

Coordinator

UNIVERSITAT LINZ

Address

Altenberger Strasse 69
4040 Linz

Austria

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 50 000

Participants (2)

BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG

Germany

EU Contribution

€ 35 000

KEPLER UNIVERSITATSKLINIKUM GMBH

Austria

EU Contribution

€ 15 000

Project information

Grant agreement ID: 800832

  • Start date

    1 July 2018

  • End date

    31 December 2019

Funded under:

H2020-EU.1.2.1.

  • Overall budget:

    € 100 000

  • EU contribution

    € 100 000

Coordinated by:

UNIVERSITAT LINZ

Austria