Skip to main content

Neural circuitry and health consequences of cognitive bias

Objective

Stress has long been a major concern among researchers interested in health and welfare. Most of their work has considered stress from either a biological or an environmental perspective, focusing on the activation of the physiological systems involved in the stress process or the role of stressful life events in specific diseases. While interesting, if we are to fully understand the effects of stress on health, we must also take into account a psychological perspective that considers an individual’s perception of stress. Indeed, a deep understanding of the neural circuitry underlying psychological stress and its physiological consequences is crucial to meaningfully explain inter-individual variations in vulneraibility to stress. In this way, my ongoing research has revealed some preliminary results which indicate ‒ for the first time ‒ that cognitive bias towards pessimistic judgments (i.e. some individuals consistently evaluate ambiguous stimuli as negative) may predict an individual’s susceptibility to the detrimental effects of chronic stress. These groundbreaking results shed light on a completely unexplored and highly promising avenue of research, based on the potential impact of evaluation biases regarding stress on an individual’s vulnerability to stress-associated diseases. In this framework, COGBIAS firstly aims to characterise the specific neural circuits underlying cognitive bias by which stress is perceived, processed, and transduced into a neuroendocrine response, using zebrafish (Danio rerio) as a model. Secondly, COGBIAS aims to unravel the role of subjective stress on resilience to stress-associated diseases. Hence, the multidisciplinary and unique perspective of this project, combining behavioural, neural, genetic, and physiological sciences, has the potential to reinforce the already European competitiveness in the area of stress-related health and management.

Field of science

  • /social sciences/psychology/psychotherapy

Call for proposal

H2020-MSCA-IF-2017
See other projects for this call

Funding Scheme

MSCA-IF-GF - Global Fellowships

Coordinator

FUNDACAO CALOUSTE GULBENKIAN
Address
Avenida Berna 45
1000 Lisboa
Portugal
Activity type
Research Organisations
EU contribution
€ 270 862,20

Partners (1)

INTER-UNIVERSITY RESEARCH INSTITUTECORPORATION RESEARCH ORGANIZATIONOF INFORMATION AND SYSTEMS
Japan
Address
Midori Cho 10-3 Tachikawa Shi
190-8518 Tokyo
Activity type
Research Organisations