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Quantitative T cell Immunology and Immunotherapy

Objective

Health and disease are regulated, to a large extent, by our immune system. The immune system not only protects the body from infectious disease, but is involved in a number of conditions of increasing incidence and morbidity, such as diabetes, rheumatoid arthritis, inflammatory bowel disease and allergies. In cancer, the immune system can be both cause and cure; it contributes to chronic inflammation that promotes tumour development, but it can also provide the ultimate weapon against metastatic disease. Thus, the development of ways to harness, direct or restrain immune responses has great potential for enhancing human health. Understanding the mechanisms that control the abundance of different lymphocyte (a type of white blood cell) subsets is key to therapeutically targeting immune responses. Ultimately, this understanding must be sought in quantitative terms, explaining how the rates of cell proliferation, differentiation, survival and death are determined by molecular mechanisms and cellular interactions. Current immunological research is beginning to combine experimental approaches with mathematical analysis to quantitate immune dynamics. A severe obstacle to more rapid progress in this area is the lack of appropriately trained scientists. In this ETN, European scientists, with a rich track record in collaborative research and training, have come together to deliver a highly collaborative, multidisciplinary and intersectoral research training programme for 15 early stage researchers (ESRs) in Quantitative T cell Immunology and Immunotherapy (QuanTII).

Coordinator

UNIVERSITY OF LEEDS
Net EU contribution
€ 819 863,64
Address
Woodhouse Lane
LS2 9JT Leeds
United Kingdom

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Region
Yorkshire and the Humber West Yorkshire Leeds
Activity type
Higher or Secondary Education Establishments
Other funding
€ 819 863,64

Participants (10)

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
Net EU contribution
€ 273 287,88
Address
South Kensington Campus Exhibition Road
SW7 2AZ London

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Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Other funding
€ 273 287,88
MEDIMMUNE LIMITED

Participation ended

United Kingdom
Net EU contribution
€ 0,00
Address
Milstein Building Granta Park
CB21 6GH Cambridge
Region
East of England East Anglia Cambridgeshire CC
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UNIVERSITEIT UTRECHT
Netherlands
Net EU contribution
€ 255 374,28
Address
Heidelberglaan 8
3584 CS Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Other funding
€ 255 374,28
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
Net EU contribution
€ 510 748,56
Address
Heidelberglaan 100
3584 CX Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Other funding
€ 510 748,56
NATIONAL UNIVERSITY OF IRELAND MAYNOOTH
Ireland
Net EU contribution
€ 265 674,60
Address
Co Kildare
W23 Maynooth

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Region
Ireland Eastern and Midland Dublin
Activity type
Higher or Secondary Education Establishments
Other funding
€ 265 674,60
NATIONAL UNIVERSITY OF IRELAND GALWAY
Ireland
Net EU contribution
€ 265 674,60
Address
University Road
H91 Galway

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Region
Ireland Eastern and Midland Dublin
Activity type
Higher or Secondary Education Establishments
Other funding
€ 265 674,60
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
Net EU contribution
€ 498 432,96
Address
Im Neuenheimer Feld 280
69120 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Other funding
€ 498 432,96
BAYER AKTIENGESELLSCHAFT
Germany
Net EU contribution
€ 498 432,96
Address
Kaiser-wilhelm-allee 1
51373 Leverkusen

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Region
Nordrhein-Westfalen Köln Leverkusen, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 498 432,96
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
Net EU contribution
€ 262 875,60
Address
Rue Michel Ange 3
75794 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 262 875,60
ASTRAZENECA UK LIMITED
United Kingdom
Net EU contribution
€ 273 287,88
Address
1 Francis Crick Avenue Cambridge Biomedical Campus
CB2 0AA Cambridge

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Region
East of England East Anglia Cambridgeshire CC
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 273 287,88