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Quantitative T cell Immunology and Immunotherapy

Objective

Health and disease are regulated, to a large extent, by our immune system. The immune system not only protects the body from infectious disease, but is involved in a number of conditions of increasing incidence and morbidity, such as diabetes, rheumatoid arthritis, inflammatory bowel disease and allergies. In cancer, the immune system can be both cause and cure; it contributes to chronic inflammation that promotes tumour development, but it can also provide the ultimate weapon against metastatic disease. Thus, the development of ways to harness, direct or restrain immune responses has great potential for enhancing human health. Understanding the mechanisms that control the abundance of different lymphocyte (a type of white blood cell) subsets is key to therapeutically targeting immune responses. Ultimately, this understanding must be sought in quantitative terms, explaining how the rates of cell proliferation, differentiation, survival and death are determined by molecular mechanisms and cellular interactions. Current immunological research is beginning to combine experimental approaches with mathematical analysis to quantitate immune dynamics. A severe obstacle to more rapid progress in this area is the lack of appropriately trained scientists. In this ETN, European scientists, with a rich track record in collaborative research and training, have come together to deliver a highly collaborative, multidisciplinary and intersectoral research training programme for 15 early stage researchers (ESRs) in Quantitative T cell Immunology and Immunotherapy (QuanTII).

Call for proposal

H2020-MSCA-ITN-2017
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Coordinator

UNIVERSITY OF LEEDS
Address
Woodhouse Lane
LS2 9JT Leeds
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 819 863,64

Participants (10)

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 273 287,88
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
MEDIMMUNE LIMITED

Participation ended

United Kingdom
EU contribution
€ 0
Address
Milstein Building Granta Park
CB21 6GH Cambridge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITEIT UTRECHT
Netherlands
EU contribution
€ 255 374,28
Address
Heidelberglaan 8
3584 CS Utrecht
Activity type
Higher or Secondary Education Establishments
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 510 748,56
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments
NATIONAL UNIVERSITY OF IRELAND MAYNOOTH
Ireland
EU contribution
€ 265 674,60
Address
Co Kildare
W23 Maynooth
Activity type
Higher or Secondary Education Establishments
NATIONAL UNIVERSITY OF IRELAND GALWAY
Ireland
EU contribution
€ 265 674,60
Address
University Road
H91 Galway
Activity type
Higher or Secondary Education Establishments
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
EU contribution
€ 498 432,96
Address
Im Neuenheimer Feld 280
69120 Heidelberg
Activity type
Research Organisations
BAYER AKTIENGESELLSCHAFT
Germany
EU contribution
€ 498 432,96
Address
Kaiser-wilhelm-allee 1
51373 Leverkusen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 262 875,60
Address
Rue Michel Ange 3
75794 Paris
Activity type
Other
ASTRAZENECA UK LIMITED
United Kingdom
EU contribution
€ 273 287,88
Address
1 Francis Crick Avenue Cambridge Biomedical Campus
CB2 0AA Cambridge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)