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Bio-orthogonal catalysis for cancer therapy

Objective

THERACAT is an international and multidisciplinary consortium aiming at the training of 13 ESRs on the innovative topic of novel bio-orthogonal catalysis-based tools for cancer therapy. This ETN comprises 6 academic partners, 3 industrial partners active in the pharmaceutical market (1 large pharmaceutical company, Teva, and 2 SMEs, BiogelX and Tagworks) and 3 partners with focus on science communication (Cancer research UK), gender and minorities (UAB-Observatory for Equality) and management and entrepreneurship (ESADE business school). The combination of academic, private and society-involved organisations will provide a broad training for the 13 ESRs recruited, equipping them with the necessary skills to succeed as scientists, industrial researchers and entrepreneurs.
The development of novel cancer therapies is a major challenge for academic research and pharmaceutical industries. THERACAT aims to establish a training programme focused on the development of THERApeutic CATalysts. In this strategy, materials bearing a catalytic unit are delivered to the tumour and subsequently non-active prodrugs are administered. The prodrugs are non-toxic and therefore generate limited side effects. Only at the tumour site the catalytic particles convert the prodrugs into active compounds that generate a therapeutic effect. This approach presents several advantages on the classical drug delivery paradigm including limited side effects and prolonged efficacy.
This multidisciplinary research programme will be the setting for the training of 13 ESRs. The combination of the research expertise, the cutting-edge facilities and the complementary skills present in the consortium holds a great promise for the advancement of their careers, as well as of the knowledge of catalysis-based anticancer therapies and the development of marketable technologies and products.

Field of science

  • /medical and health sciences/clinical medicine/cancer
  • /social sciences/economics and business/business and management/commerce

Call for proposal

H2020-MSCA-ITN-2017
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks
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Coordinator

FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Address
Carrer Baldiri Reixac Planta 2A 10-12
08028 Barcelona
Spain
Activity type
Research Organisations
EU contribution
€ 247 872,96

Participants (8)

TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
EU contribution
€ 758 603,49
Address
Groene Loper 3
5612 AE Eindhoven
Activity type
Higher or Secondary Education Establishments
RIJKSUNIVERSITEIT GRONINGEN
Netherlands
EU contribution
€ 255 374,28
Address
Broerstraat 5
9712CP Groningen
Activity type
Higher or Secondary Education Establishments
UNIVERSITAT BASEL
Switzerland
EU contribution
€ 265 226,76
Address
Petersplatz 1
4051 Basel
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 546 575,76
Address
Old College, South Bridge
EH8 9YL Edinburgh
Activity type
Higher or Secondary Education Establishments
TEL AVIV UNIVERSITY
Israel
EU contribution
€ 520 601,04
Address
Ramat Aviv
69978 Tel Aviv
Activity type
Higher or Secondary Education Establishments
TEVA PHARMACEUTICAL INDUSTRIES LIMITED
Israel
EU contribution
€ 260 300,52
Address
5 Basel St
49131 Petach Tivka
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
TAGWORKS PHARMACEUTICALS BV
Netherlands
EU contribution
€ 255 374,28
Address
Vondellaan 11
5611 NX Eindhoven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BIOGELX LIMITED
United Kingdom
EU contribution
€ 273 287,88
Address
Biocity Scotland Bo'ness Road Lanarkshire
ML1 5UH Newhouse
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)