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Prostate Cancer DIagnOsis and TreatmeNt Enhancement through the Power of Big Data in EuRope

Objective

Prostate Cancer (PCa) is the second leading cause of cancer, among men in Europe. There are currently major unmet needs in this field, such as insufficient knowledge on risk factors that contribute to PCa and on patient characteristics (including genetic profiles) that could facilitate patient stratification. Finally, there is lack of meaningful engagement of all key stakeholders, while the knowledge currently gained from clinical practice and real life data is not being fed back into PCa patients’ care pathways. There is thus a need for better definition of PCa across all stages, improved patient’s stratification at diagnosis, and standardisation of PCa-related outcomes based on real life data.

PIONEER’s unique dual approach is to first identify critical evidence gaps in PCa by respected Key Opinion Leaders, and then embark on a research priority setting exercise that reflects the needs of all key stakeholders in PCa management. To achieve this, PIONEER has brought together comprehensive datasets that consists of the most relevant prostate clinical trials and registries, large epidemiological cohorts, electronic heath records, and real-life data from different European (and non-European) patient populations. These unique data sets will be integrated, standardised, harmonised and analysed using approaches that are built on our experience of similar previous IMI projects i.e EMIF, and eTRIKS, and analysed using a unique set of methodologies and advanced analytics methods (OMOP, eHS). PIONEER has already performed a first PCa research priority setting survey, where major stakeholders were asked to identify the current unmet needs in PCa. The five most important open questions will be used as pilot studies to verify PIONEER’s research framework. As such, PIONEER’s deliverables will be outcome-driven, value-based and patient-centric, and relevant to all key stakeholders, as they would have been meaningfully involved from the inception of the project.

Call for proposal

H2020-JTI-IMI2-2016-10-two-stage
See other projects for this call

Funding Scheme

IMI2-RIA - Research and Innovation action

Coordinator

STICHTING EUROPEAN UROLOGICAL FOUNDATION
Address
Mr. E.n. Van Kleffenstraat 5
6842 CV Arnhem
Netherlands
Activity type
Other
EU contribution
€ 400 000

Participants (33)

LUNDS UNIVERSITET
Sweden
EU contribution
€ 185 761,25
Address
Paradisgatan 5C
22100 Lund
Activity type
Higher or Secondary Education Establishments
UNIVERSITA VITA-SALUTE SAN RAFFAELE
Italy
EU contribution
€ 312 500
Address
Via Olgettina 58
20132 Milano
Activity type
Higher or Secondary Education Establishments
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 350 000
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
Germany
EU contribution
€ 150 000
Address
Martinistrasse 52
20251 Hamburg
Activity type
Higher or Secondary Education Establishments
TAMPEREEN KORKEAKOULUSAATIO SR
Finland
EU contribution
€ 387 500
Address
Kalevantie 4
33100 Tampere
Activity type
Higher or Secondary Education Establishments
KING'S COLLEGE LONDON
United Kingdom
EU contribution
€ 350 000
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
EUROPEAN ORGANISATION FOR RESEARCH AND TREATMENT OF CANCER AISBL
Belgium
EU contribution
€ 200 000
Address
Avenue E. Mounier 83
1200 Brussels
Activity type
Research Organisations
TTOPSTART BV
Netherlands
EU contribution
€ 225 000
Address
Euclideslaan 1
3584 BL Utrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INTERNATIONAL CONSORTIUM FOR HEALTHOUTCOMES MEASUREMENT LTD
United Kingdom
EU contribution
€ 61 250
Address
1 Eversholt Street
NW1 2DN London
Activity type
Other
EUROPEAN CANCER PATIENT COALITION
Belgium
EU contribution
€ 79 993,75
Address
Rue Montoyer 40
1000 Bruxelles
Activity type
Other
ASSOCIATION EISBM
France
EU contribution
€ 700 000
Address
7 Parc Des Cedres 11 Rue Jean Marie Chevalier
69390 Vourles
Activity type
Research Organisations
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 529 995
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
THE HYVE BV
Netherlands
EU contribution
€ 400 000
Address
Arthur Van Schendelstraat 650
3511 MJ Utrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EUROPEAN ALLIANCE FOR PERSONALISED MEDICINE ASBL
Belgium
EU contribution
€ 180 000
Address
Rue De L Aqueduc 88A
1050 Bruxelles
Activity type
Research Organisations
PINSENT MASONS LLP
United Kingdom
EU contribution
€ 150 000
Address
Earl Street 30 Crown Place
EC2A 4ES London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CANCER INTELLIGENCE LIMITED

Participation ended

United Kingdom
EU contribution
€ 12 121,34
Address
11 Alma Vale Rd
BS8 2HL Bristol
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 200 000
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
United Kingdom
EU contribution
€ 353 000
Address
King's College Regent Walk
AB24 3FX Aberdeen
Activity type
Higher or Secondary Education Establishments
TECHNISCHE UNIVERSITAET DRESDEN
Germany
EU contribution
€ 125 000
Address
Helmholtzstrasse 10
01069 Dresden
Activity type
Higher or Secondary Education Establishments
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 125 000
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations
GOETEBORGS UNIVERSITET
Sweden
EU contribution
€ 150 000
Address
Vasaparken
405 30 Goeteborg
Activity type
Higher or Secondary Education Establishments
STICHTING RADBOUD UNIVERSITEIT
Netherlands
EU contribution
€ 150 000
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
IHE, INSTITUTET FOR HALSO- OCH SJUKVARDSEKONOMI AKTIEBOLAG
Sweden
EU contribution
€ 175 000
Address
Rabygatan 2, 3Tr
223 61 Lund
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BAYER AKTIENGESELLSCHAFT
Germany
EU contribution
€ 0
Address
Kaiser-wilhelm-allee 1
51373 Leverkusen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT
France
EU contribution
€ 0
Address
Pierre Brossolette 1
91380 Chilly Mazarin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
VARIAN MEDICAL SYSTEM DEUTSCHLAND GMBH

Participation ended

Germany
EU contribution
€ 0
Address
Alsfelder Strasse 6
64289 Darmstadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ASTELLAS PHARMA EUROPE BV
Netherlands
EU contribution
€ 0
Address
Sylviusweg 84
2333 BE Leiden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NV SAS INSTITUTE SA
Belgium
EU contribution
€ 0
Address
Hertenbergstraat 6
3080 Tervuren
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
JANSSEN PHARMACEUTICA NV
Belgium
EU contribution
€ 0
Address
Turnhoutseweg 30
2340 Beerse
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
COVANCE LABORATORIES LTD
United Kingdom
EU contribution
€ 0
Address
Otley Road
HG3 IPY Harrogate
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ORION OYJ
Finland
EU contribution
€ 0
Address
Orionintie 1
02200 Espoo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
IMS INFORMATION SOLUTIONS MEDICAL RESEARCH LIMITED
United Kingdom
EU contribution
€ 0
Address
Pentonville Road 210
NI 9JY London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE ECANCER GLOBAL FOUNDATION
United Kingdom
EU contribution
€ 47 878,66
Address
13 King Square Avenue
BS2 8HU Bristol
Activity type
Other