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Building the product pipeline for commercial demonstration of Plant Molecular Factories

Objective

Plant Molecular Farming is the manufacture of high-value products using plant biotechnology. Pharma-Factory was conceived and designed by SMEs active in the field to produce medical, veterinary and diagnostic products. Product-driven work packages and a collective approach to public involvement and regulatory consultation will accelerate commercialisation of new bio-products, and increase the competitiveness of European bio-industry by resolving technical, social and economic bottlenecks in this field. All parts of the work programme are addressed by refining technologies using new synthetic biology tools, demonstrating manufacturing advantages for individual products, identifying a clear regulatory path for each platform technology, developing clear business cases with supporting techno-economic evaluations and life cycle analyses and improving public engagement and acceptance. Five SMEs will develop products that include arylsulfatase B (for human enzyme replacement therapy), a vaccine for infectious spleen and kidney necrosis virus in fish, two highly potent HIV neutralising antibody-based fusion proteins and plant chimaeric virus-like-particles for a diagnostic kit. In collaboration with academic partners they will advance six plant molecular farming platforms for this purpose, including whole plants, algae, hairy roots and plant cell culture, by designing and developing new tools to increase the competitiveness, utility and versatility of each platform. All companies will reach Technology Readiness Level 5 within the lifetime of the project, with two products to be commercialized. The project provides a unique opportunity to improve public involvement with plant biotechnology at a European-wide level. A work package has been dedicated to gain maximal impact by engaging with all stakeholders – from scientists to government and the public at large, developing new tools to facilitate communication, to help understand and reduce barriers to acceptance.

Field of science

  • /natural sciences/biological sciences/synthetic biology
  • /social sciences/economics and business
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins
  • /natural sciences/biological sciences/microbiology/phycology
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes
  • /agricultural sciences/animal and dairy science

Call for proposal

H2020-BB-2017-1
See other projects for this call

Funding Scheme

IA - Innovation action

Coordinator

ST GEORGE'S HOSPITAL MEDICAL SCHOOL
Address
Cranmer Terrace
SW17 0RE London
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 715 885

Participants (13)

DIAMANTE SRL
Italy
EU contribution
€ 499 625
Address
Strada Le Grazie 15
37134 Verona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITE DE ROUEN NORMANDIE
France
EU contribution
€ 531 500
Address
Rue Thomas Becket 1 Mont Saint Aignan
76821 Mont Saint Aignan Cedex
Activity type
Higher or Secondary Education Establishments
ALBAJUNA THERAPEUTICS
Spain
EU contribution
€ 400 312,50
Address
Ctra Del Canyet, S/n, Hospital Germans Trias I Pujol, 2 Planta
08916 Badalona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LEAF SYSTEMS INTERNATIONAL LIMITED
United Kingdom
EU contribution
€ 384 040,13
Address
Building 7, Zone 2, Norwich Research Park, Colney Lane, Colney
NR47UJ Norwich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
TRANSALGAE ISRAEL LTD
Israel
EU contribution
€ 519 750
Address
2 Haim Pekeris Street
7670202 Tehovot
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSIDAD DE LLEIDA
Spain
EU contribution
€ 519 902,50
Address
Placa Victor Siurana 1 1
25003 Lleida
Activity type
Higher or Secondary Education Establishments
SAMABRIVA
France
EU contribution
€ 455 700
Address
72 Rue Des Jacobins
80000 Amiens
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
JOHN INNES CENTRE
United Kingdom
EU contribution
€ 509 982,50
Address
Norwich Research Park Colney
NR4 7UH Norwich
Activity type
Research Organisations
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 519 710
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
THE UNIVERSITY OF THE ARTS LONDON
United Kingdom
EU contribution
€ 520 000
Address
272 High Holburn
WC1V 7EY London
Activity type
Higher or Secondary Education Establishments
UNIVERSITY COLLEGE LONDON
United Kingdom
EU contribution
€ 524 226
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
Teknologian tutkimuskeskus VTT Oy
Finland
EU contribution
€ 560 827,50
Address
Vuorimiehentie 3
02150 Espoo
Activity type
Research Organisations
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 624 547,50
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations