Cardiovascular diseases are the first cause of deaths globally and an economic burden and they are commonly treated by surgery. However, surgeons still lack precise knowledge about what they will face in the operating room, increasing medical errors and associated morbidity and mortality. MedicalPhant is a new system for the printing of the most accurate customized 3D replicas of complex cardiovascular pathologies and structures. It uses CT/MRI/Echo images from a patient to virtual modelling and to print a 3D model with suitable materials. Our system can greatly reduce medical errors, times, hospitalization and costs of cardiac surgery and improve final outcomes, specialists’ performance and patient’s quality of life. MedicalPhant is at a TRL6, preliminary developed and validated, and now we aim to optimized it and validate it in a clinical study, scale-up the production, establish a sales team and reach potential users (hospitals, MedTech companies, etc.). We plan to obtain part of the necessary founding by applying to a H2020 SME-Instrument Phase 2 grant.