Project description DEENESFRITPL Unravelling early-life factors linked to suicidal ideation, suicide attempts, and suicide Around 700 000 people take their lives every year – one person every 40 seconds. More and more studies suggest that ‘early-life’ events, those occurring before or around birth, can influence later susceptibility to suicide. With the support of the Marie Skłodowska-Curie Actions programme, the LIFESPAN project will investigate the potential link between birth order, parental age, family/sibling size, birth weight, and birth length on suicide, suicidal ideation and suicide attempts in the general population. This will be accomplished with meta-analyses of longitudinal studies and longitudinal mediation analysis techniques relying on growth curve modelling to identify specific mediating pathways (targetable with new preventive interventions) linking early-life factors and suicide risk. Show the project objective Hide the project objective Objective Suicide is a major public health concern and leading cause of death worldwide. Suicidal ideation and attempts, especiallyamong youths, are of particular concern because of their associations with suicide, poor health, educational and employmentoutcomes. The World Health Organisation European Mental Health Action Plan has ranked suicide prevention among thehighest priorities on the global public health agenda for 2020. While recognising the importance of immediate precipitatingfactors (unemployment, relationship problems), studies worldwide are showing that early-life events, occurring before oraround birth, can influence later susceptibility to suicide. The LIFESPAN project adopts a life-course perspective to examinethe early-life influences (birth order, parental age, family/sibling size, birth weight, birth length) on suicide, suicidal ideationand suicide attempts in the general population. It comprises 3 complementary objectives: (1) to summarise available studiesabout the longitudinal relations between early-life influences and suicide mortality by applying meta-analysis, the statisticalapproach most informative for policymakers, allowing to go beyond the heterogeneity of existing studies; (2) to investigatethe associations between early-life influences and suicidal ideation and attempts in adolescence and young adulthood withdata from 3 longitudinal population-based cohorts (from Canada and France; up to 25 years follow-up); (3) to identify specificmediating pathways (targetable with new preventive interventions) linking early-life factors and suicide risk, using advanceslongitudinal mediation analysis techniques relying on growth curve modelling. By shedding new light on the role of early-lifeinfluence on suicidality, this project will contribute to the H2020 aim of “promoting healthy ageing and personalised healthcare [which] will enable to better understand the determinants of health, keep the population healthier, preserve quality oflife”. Fields of science medical and health scienceshealth sciencespublic healthmedical and health sciencesclinical medicinepsychiatrynatural sciencesmathematicsapplied mathematicsstatistics and probabilitysocial sciencespsychologydevelopmental psychology Keywords suicide suicidal ideation suicide attempts life-course perspective mediation mechanisms developmental approach Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2017 - Individual Fellowships Call for proposal H2020-MSCA-IF-2017 See other projects for this call Funding Scheme MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF) Coordinator UNIVERSITE DE BORDEAUX Net EU contribution € 232 160,40 Address PLACE PEY BERLAND 35 33000 Bordeaux France See on map Region Nouvelle-Aquitaine Aquitaine Gironde Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 232 160,40 Partners (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING MCGILL UNIVERSITY Canada Net EU contribution € 0,00 Address 845 SHERBROOKE STREET WEST H3A0G4 Montreal See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 145 622,40
