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Overcoming specific weaknesses in tendon biology to design advanced regenerative therapies

Description du projet

DEENESFRITPL

Améliorer la recherche sur l’ingénierie tissulaire des tendons au Portugal

Les tendons sont les tissus fibreux souples et résistants qui relient les muscles aux os. En cas de blessure, ils subissent une inflammation et engendrent des douleurs et une invalidité. Les stratégies de réparation actuelles impliquent principalement la chirurgie, mais les résultats cliniques sont médiocres, ce qui impose d’avoir recours à des approches alternatives. L’ingénierie tissulaire apparaît comme une stratégie prometteuse de reconstruction des tendons blessés, ce qui suppose toutefois une meilleure connaissance de la biophysique et de la biologie des tendons. L’objectif du projet Achilles, financé par l’UE, est de renforcer la capacité de recherche du groupe de recherche 3B de l’université de Minho (UMinho), au Portugal, dans le domaine de l’ingénierie tissulaire des tendons. De plus, son jumelage avec d’autres institutions partenaires devrait permettre à Achilles d’accroître la visibilité internationale et la capacité de mise en réseau de l’UMinho.

Objectif

The main goal of Achilles is to significantly strengthen the science and technology capacity of UMinho in biophysics, cell/molecular biology and genetics/gene therapy in order to achieve global scientific excellence and competitiveness for the translation of advanced therapies/ tendon tissue engineering strategies to treat tendon injuries/diseases; At the same tine, Achilles also aims at positioning the research profile of UMinho and its staff in an outstanding international research level. This will be achieved by establishing a twinning process through knowledge sharing and collaboration between 3B’s Research Group of University of Minho (UMinho) and 2 internationally leading institutions: Department of Trauma Surgery of the University Regensburg Medical Centre (UHREG) and the Regenerative, Modular & Developmental Engineering Laboratory of the National University of Ireland Galway (NUIG). Achilles will focus in defined areas in which UMinho shows a less scientific knowledge and are well-complemented by UHREG and NUIG. The project objectives are:
- To significantly increase the scientific excellence in tendon tissue engineering and reinforce human resources profile of UMinho;
- To significantly increase the international visibility of UMinho and unleash its networking gaps with international outstanding R&D organisations;
- To create strong links between UMinho-UHREG-NUIG allowing a constant and sustained knowledge sharing and research collaboration network which will continue sustainably in the long-term;
- To significantly increase the capacity of UMinho to translate excellent scientific production into new therapeutic approaches for the treatment of tendon disorders and in providing high-quality services and consulting, improved capability to compete for funding as well as generating useful intellectual property that can help to support in the long-term the sustainability of the organization.

Champ scientifique

Mots‑clés

Programme(s)

Thème(s)

Appel à propositions

H2020-WIDESPREAD-2016-2017

Voir d’autres projets de cet appel

Sous appel

H2020-WIDESPREAD-05-2017-Twinning

Régime de financement

CSA - Coordination and support action

Coordinateur

UNIVERSIDADE DO MINHO
Contribution nette de l'UE
€ 500 601,25
Adresse
LARGO DO PACO
4704 553 Braga
Portugal

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Région
Continente Norte Cávado
Type d’activité
Higher or Secondary Education Establishments
Liens
Coût total
€ 500 601,25

Participants (4)

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Dernière mise à jour: 13 Juin 2023

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Permalink: https://cordis.europa.eu/project/id/810850/fr

European Union, 2024