PermeAbility - A non-invasive, side-effect-free diagnostic kit for intestinal disorders

Projektinformationen

PermeAbility

ID Finanzhilfevereinbarung: 828547

DOI 10.3030/828547

Abgeschlossenes Projekt

EK-Unterschriftsdatum 20 Juli 2018

Startdatum 1 August 2018

Enddatum 31 Januar 2019

Finanziert unter

• INDUSTRIAL LEADERSHIP - Innovation In SMEs

Gesamtkosten € 71 429,00

EU-Beitrag € 50 000,00

Koordiniert durch

LIEFTAG LDA
Portugal

Ziel

"Inflammatory Bowel Disease (IBD) is a form of acute inflammation to the small intestine that causes ulcers and extensive damage of the gut barrier causing it to rupture. This causes bleedings, abdominal pain, diarrhea, and a dramatic reduction of the quality of life. The intestinal barrier is normally a very well organised structure in which the cells are tightly connected maintaining the barrier. Moreover, IBD lesions compromise this intestinal organization and increases intestinal permeability, which is called leaky gut syndrome (LGS) being also a pre-disposing factor for several other health problems. LGS compromises digestion of food particles and removal of toxic waste products, and allows bacteria to ""leak"" through the intestine to the blood stream. Besides in IBD, LGS is also common in people with health conditions such as obesity, rheumatoid arthritis and type 2 diabetes. Even though IBD poses significant threats to a patients’ health and a heavy direct and indirect economic burden, diagnosis of this condition is still limited assessing indirect parameters like general inflammation markers in plasma and stool and evaluation based by comparison on the patients symptoms description. The direct measures are also performed but are restricted to very invasive methods like biopsy or solely qualitative like MRI and microcapsule colonoscopy. In this way it is reported in several clinical articles a clear need for new diagnostic methods in IBD reinforced by facts like 35% of the performed surgeries for treatment revealing unnecessary and 1.9 billion people worldwide at risk for early lesions and IBD development not being diagnosed. In this way clinical practice urges for new methods for the assessment of lesions in the intestinal wall. Lifetag’s has developed PermeAbility, a new proprietary test to measure intestinal permeability to better select patients at high risk of IBD , leading to better informed clinical decision making, diagnosis, and treatment."

Wissenschaftliches Gebiet

• medical and health sciences › clinical medicine › rheumatology
• medical and health sciences › clinical medicine › surgery
• medical and health sciences › clinical medicine › gastroenterology › inflammatory bowel disease
• medical and health sciences › clinical medicine › endocrinology › diabetes
• medical and health sciences › health sciences › nutrition › obesity

Programm/Programme

• H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs Main Programme
• H2020-EU.3. - PRIORITY 'Societal challenges
• H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies

Thema/Themen

• EIC-SMEInst-2018-2020 - SME instrument

Aufforderung zur Vorschlagseinreichung

H2020-EIC-SMEInst-2018-2020

Andere Projekte für diesen Aufruf anzeigen

Unterauftrag

H2020-SMEInst-2018-2020-1

Finanzierungsplan

SME-1 - SME instrument phase 1

Koordinator

LIEFTAG LDA

• Netto-EU-Beitrag: € 50 000,00
• Adresse: BIOCANT - ASSOCIACAO DE TRANSFERENCIA DE TECNOLOGI ; 3060 197 CANTANHEDE ; Portugal
• KMU Die Organisation definierte sich zum Zeitpunkt der Unterzeichnung der Finanzhilfevereinbarung selbst als KMU (Kleine und mittlere Unternehmen). Ja:
  Region
  Continente › Centro (PT) › Região de Coimbra
• Region: Continente › Centro (PT) › Região de Coimbra
• Aktivitätstyp: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Gesamtkosten: € 71 429,00