Skip to main content

iFERMENTER - CONVERSION OF FORESTRY SUGAR RESIDUAL STREAMS TO ANTIMICROBIAL PROTEINS BY INTELLIGENT FERMENTATION

Objective

Plant dry matter, so-called lignocellulosic biomass, is the largest renewable biomass feedstock on Earth. Europe has over 14 mill tons of sugar residuals from biorefineries, which could be converted to profitable products and contribute to a sustainable bioeconomy. Unfortunately, existing biorefineries struggle with technical issues and low profitability due to the lack of adequate fermentation processes. Therefore, these sugars are either incinerated to generate energy or at best converted to ethanol (€0.6 /kg) but not to higher value chemicals.
Current concepts that aim to establish fermentation processes to convert residual sugar streams to high value products face challenges including inefficient sugar utilization by microorganisms and inhibitors in the residual streams, leading to low productivity and yields.
Our project aims to recover high value compounds from sugar residuals, and to turn fermentation processes converting these residual to antimicrobials cost effective. We will recover the high value sugar galactose (€40-200 /kg) from residual streams as part of their treatment process. By genome editing technique, we will design cell factories that consume the remaining residuals and produce nisin (€50-150 /kg), an industrially important commercial food/feed preservative. Additionally, we will develop an affordable, online feedback add-on system that will allow to intelligently change residual mixture during fermentation of these cell factories to optimize production online during the process. In a 150 L industrial bioreactor, we will demonstrate that our add-on invention iFermenter
- increases the yields of nisin by over 2 fold
- increases the nisin production by over 50% compared to what is possible today,
- and reduce at least 20% in CO2 footprint with this process compared to existing solutions.
Thus, iFermenter will render production of high value products with residual sugar stream highly efficient and cost-effective contributing to circular economy.

Field of science

  • /engineering and technology/industrial biotechnology/bioprocessing technologies/fermentation
  • /agricultural sciences/agricultural biotechnology/biomass

Call for proposal

H2020-BBI-JTI-2017
See other projects for this call

Funding Scheme

BBI-RIA - Bio-based Industries Research and Innovation action

Coordinator

NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU
Address
Hogskoleringen 1
7491 Trondheim
Norway
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 928 150

Participants (11)

UNIVERSITAET ULM
Germany
EU contribution
€ 409 875
Address
Helmholtzstrasse 16
89081 Ulm
Activity type
Higher or Secondary Education Establishments
UNIVERSITAT DES SAARLANDES
Germany
EU contribution
€ 613 875
Address
Campus
66123 Saarbrucken
Activity type
Higher or Secondary Education Establishments
TECHNISCHE UNIVERSITAET WIEN
Austria
EU contribution
€ 673 266,25
Address
Karlsplatz 13
1040 Wien
Activity type
Higher or Secondary Education Establishments
BIO BASE EUROPE PILOT PLANT VZW
Belgium
EU contribution
€ 438 473,75
Address
Rodenhuizekaai 1
9042 Desteldonk Gent
Activity type
Other
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
Spain
EU contribution
€ 179 390
Address
Colexio De San Xerome Praza Do Obradoiro S/n
15782 Santiago De Compostela
Activity type
Higher or Secondary Education Establishments
NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET
Norway
EU contribution
€ 146 500
Address
Universitetstunet 3
1433 As
Activity type
Higher or Secondary Education Establishments
BORREGAARD AS
Norway
EU contribution
€ 0
Address
Hjalmar Wessels Vei 6
1721 Sarpsborg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
GALACTIC SA
Belgium
EU contribution
€ 0
Address
Place D'escanaffles 23
7760 Escanaffles
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MYBIOTECH GMBH
Germany
EU contribution
€ 128 025
Address
Industriestrasse 1B
66802 Uberherrn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INFORS AG
Switzerland
EU contribution
€ 229 875
Address
Rittergasse 27
4103 Bottmingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 250 395
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments