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Strengthening the Research Area of Delivery of Nucleic acid mimics (NAMS) into bacteria to fight the antibiotic crisis

Strengthening the Research Area of Delivery of Nucleic acid mimics (NAMS) into bacteria to fight the antibiotic crisis

Objective

DelNAM aims at Strengthening the Research Area of Delivery of Nucleic Acid Mimics (NAMS) into bacteria to fight the antibiotic crisis. This will be achieved by twinning the Faculty of Engineering of the University of Porto (FEUP) with outstanding EU institutions with high expertise in the areas of NAMs development and nanodelivery strategies. DelNAM will allow the development of a consolidated strategic research approach and a set of guidelines for exploitation and commercialization of the results that will have a strong regional, national and European impact. The proposal integrates synergies in complementary fields of research that include nanotechnology, synthetic chemistry, microbiology and bioprocess modelling, aiming to obtain scientific breakthroughs that can improve the global health and economy.

The objectives of this proposal are in line with the specific challenge and scope of the topic H2020-WIDESPREAD-2016-2017 of the Twinning call, addressing networking gaps and deficiencies between the research institutions of the Widening countries and internationally-leading counterparts at EU level. This challenge is addressed by twinning FEUP with 2 leading EU research institutions: University of Southern Denmark (SDU), in Odense, Denmark, a global leader in the development and invention of novel NAMs for gene therapy. They contribute with their extensive experience on the synthesis, structural studies and molecular modelling of NAMs; Ghent University (UGhent), in Belgium, an internationally-recognized laboratory for its excellence in the field of nanomedicines for the delivery of drugs and, in particular, nucleic acids. They provide decisive expertise on the design of delivery systems for nucleic acids and their behavior in native biological fluids.
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Coordinator

UNIVERSIDADE DO PORTO

Address

Praca Gomes Teixeira
4099 002 Porto

Portugal

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 475 978,75

Participants (2)

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SYDDANSK UNIVERSITET

Denmark

EU Contribution

€ 246 125

UNIVERSITEIT GENT

Belgium

EU Contribution

€ 238 750

Project information

Grant agreement ID: 810685

Status

Ongoing project

  • Start date

    1 August 2018

  • End date

    31 July 2021

Funded under:

H2020-EU.4.b.

  • Overall budget:

    € 960 853,75

  • EU contribution

    € 960 853,75

Coordinated by:

UNIVERSIDADE DO PORTO

Portugal