Strengthening the Research Area of Delivery of Nucleic acid mimics (NAMS) into bacteria to fight the antibiotic crisis

Objective

DelNAM aims at Strengthening the Research Area of Delivery of Nucleic Acid Mimics (NAMS) into bacteria to fight the antibiotic crisis. This will be achieved by twinning the Faculty of Engineering of the University of Porto (FEUP) with outstanding EU institutions with high expertise in the areas of NAMs development and nanodelivery strategies. DelNAM will allow the development of a consolidated strategic research approach and a set of guidelines for exploitation and commercialization of the results that will have a strong regional, national and European impact. The proposal integrates synergies in complementary fields of research that include nanotechnology, synthetic chemistry, microbiology and bioprocess modelling, aiming to obtain scientific breakthroughs that can improve the global health and economy.

The objectives of this proposal are in line with the specific challenge and scope of the topic H2020-WIDESPREAD-2016-2017 of the Twinning call, addressing networking gaps and deficiencies between the research institutions of the Widening countries and internationally-leading counterparts at EU level. This challenge is addressed by twinning FEUP with 2 leading EU research institutions: University of Southern Denmark (SDU), in Odense, Denmark, a global leader in the development and invention of novel NAMs for gene therapy. They contribute with their extensive experience on the synthesis, structural studies and molecular modelling of NAMs; Ghent University (UGhent), in Belgium, an internationally-recognized laboratory for its excellence in the field of nanomedicines for the delivery of drugs and, in particular, nucleic acids. They provide decisive expertise on the design of delivery systems for nucleic acids and their behavior in native biological fluids.

Field of science

• /social sciences/economics and business/business and management/innovation management
• /medical and health sciences/health sciences/public and environmental health
• /natural sciences/biological sciences/microbiology/bacteriology
• /medical and health sciences/basic medicine/pharmacology and pharmacy/drug resistance/antibiotic resistance
• /medical and health sciences/medical biotechnology/genetic engineering/gene therapy
• /natural sciences/biological sciences/biochemistry/biomolecules/nucleic acid

Programme(s)

• H2020-EU.4.b. - Twinning of research institutions

Topic(s)

• WIDESPREAD-05-2017 - Twinning

Call for proposal

H2020-WIDESPREAD-05-2017-Twinning
See other projects for this call

Funding Scheme

CSA - Coordination and support action

Coordinator

UNIVERSIDADE DO PORTO

Address

Praca Gomes Teixeira
4099 002 Porto
Portugal

Activity type

Higher or Secondary Education Establishments

EU contribution

€ 475 978,75

Participants (2)

SYDDANSK UNIVERSITET

Denmark

EU contribution

€ 246 125

Address

Campusvej 55
5230 Odense M

Activity type

Higher or Secondary Education Establishments

UNIVERSITEIT GENT

Belgium

EU contribution

€ 238 750

Address

Sint Pietersnieuwstraat 25
9000 Gent

Activity type

Higher or Secondary Education Establishments