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Interdisciplinary training network for advancing Organ-on-a-chip technology in Europe

Project information

Grant agreement ID: 812954

Status

Ongoing project

  • Start date

    1 December 2018

  • End date

    30 November 2022

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 942 860,76

  • EU contribution

    € 3 942 860,76

Coordinated by:

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Germany

Objective

EUROoC will create a trans-European network of industrially oriented specialists fully trained in development and application of the emerging Organ-on-a-chip (OoC) technology. OoC technology is advancing at breath taking pace due to its potential impact in drug development and personalised treatments of disease. New researchers entering this field must be equipped with a multidisciplinary background ranging from biology to microfluidic chip engineering. EUROoC will offer the first complete and coherent European training program on OoC by gathering multidisciplinary participants (biologists, physicists, chemists, engineers) in a multi-sectoral network composed of 4 companies (3 SMEs), 2 regulation entities and 10 academic institutions. EUROoC will qualify the next generation of interdisciplinary scientists for all aspects of OoC development and utilisation, including understanding of commercialisation pathways and regulatory aspects. EUROoC furthermore comprises a collection of innovative research projects addressing the development of advanced OoC systems with higher physiological significance going beyond current in vitro testing. The EUROoC project will create advanced OoCs, which closely recapitulate properties of the respective organ tissues in vivo regarding cell types, microenvironment, organ-specific tissue structure and function as well as concepts for the interconnection of individual OoCs. The various OoC models to be developed comprise heart-on-a-chip, bone-on-a-chip, retina-on-a-chip, lung-on-a-chip, adipose- on-a-chip, gut-on-a-chip to liver-on-a-chip. The OoC systems will be able to monitor and analyse tissue functionality and response in situ by integrating various novel sensing elements. The OoCs developed will be pre-validated with the regulatory partners through in vitro-in vivo correlations. The research and training program planned will increase European competitiveness sustainably in this emerging key technology.

Coordinator

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Address

Hansastrasse 27c
80686 Munchen

Germany

Activity type

Research Organisations

EU Contribution

€ 505 576,80

Participants (10)

Universitätsklinikum Jena

Germany

EU Contribution

€ 505 576,80

TECHNISCHE UNIVERSITAET GRAZ

Austria

EU Contribution

€ 528 414,48

UNIVERSITAET BERN

Switzerland

EU Contribution

€ 281 276,64

UPPSALA UNIVERSITET

Sweden

EU Contribution

€ 281 982,96

UNIVERSITEIT TWENTE

Netherlands

EU Contribution

€ 265 619,88

ACADEMISCH ZIEKENHUIS LEIDEN

Netherlands

EU Contribution

€ 531 239,76

UNIVERSITE DU LUXEMBOURG

Luxembourg

EU Contribution

€ 256 320

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

Switzerland

EU Contribution

€ 281 276,64

BUNDESINSTITUT FUER RISIKOBEWERTUNG

Germany

EU Contribution

€ 252 788,40

MILTENYI BIOTEC GMBH

Germany

EU Contribution

€ 252 788,40

Partners (10)

EBERHARD KARLS UNIVERSITAET TUEBINGEN

Germany

ASTRAZENECA UK LIMITED

United Kingdom

UNIVERSITAT BASEL

Switzerland

BUNDESINSTITUT FUR ARZNEIMITTEL UND MEDIZINPRODUKTE

Germany

STICHTING INSTITUTE FOR HUMAN ORGAN AND DISEASE MODEL TECHNOLOGIES

Netherlands

BOEHRINGER INGELHEIM PHARMA GMBH &CO KG

Germany

TRANSGENE SA

France

UPM-KYMMENE OYJ

Finland

RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU

Netherlands

PYRO SCIENCE GMBH

Germany

Project information

Grant agreement ID: 812954

Status

Ongoing project

  • Start date

    1 December 2018

  • End date

    30 November 2022

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 942 860,76

  • EU contribution

    € 3 942 860,76

Coordinated by:

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Germany