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Identification and Management of Patients at Risk – Outcome and Vascular Events in Peritoneal Dialysis

Objective

Peritoneal dialysis (PD) is an underused life saving renal replacement therapy for end-stage kidney disease. Nevertheless, PD patients remain at high risk for poor outcome, most notably excessive risk of cardiovascular disease. There is an unmet need for a risk-adjusted individualized PD approach. The IMPROVE-PD consortium provides 15 Early Stage Researchers (ESRs) in 11 partner institutes located in 7 different countries a state-of-the-art, multidisciplinary and intersectoral pan- European training programme including input from academic, clinical and industrial stakeholders. Network-wide and local training activities, individual research projects, intersectoral secondments and short laboratory visits will provide key generic skills and will prepare ESRs for future roles as highly skilled researchers in Europe. Well-phenotyped patient cohorts, and novel experimental models and techniques will be exploited by the ESRs, mentored by an excellent supervisory team, to improve future management of the PD patient at risk. This joint effort encourages productive collaboration between industrial and academic sectors though integrated projects and shared goals. Key findings will be communicated to a broad range of stakeholders through state of the art methods. IMPROVE-PD will give rise to a new generation of experts in PD with outstanding interdisciplinary research skills, intersectoral understanding and with perspective to pursue their careers in this scientific and industrial field. It will enable timely identification of the PD patient at high risk for adverse outcome, develop understanding of underlying pathomechanisms, and within an iterative process between research groups foster the development of innovative approaches to individualized treatment by targeting revealed pathomechanisms. Through these approaches, the ITN will achieve refinement of PD fluids, PD therapy and cardiovascular risk reduction.
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Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Address

Calle Serrano 117
28006 Madrid

Spain

Activity type

Research Organisations

EU Contribution

€ 501 809,76

Participants (10)

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CARDIFF UNIVERSITY

United Kingdom

EU Contribution

€ 606 345,12

BAXTER MEDICAL PRODUCTS GMBH

Austria

EU Contribution

€ 264 207,24

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

EU Contribution

€ 274 802,04

UNIVERSITY OF KEELE

United Kingdom

EU Contribution

€ 303 172,56

EPSILON 3 GMBH

Austria

EU Contribution

€ 264 207,24

UNIVERSITE CATHOLIQUE DE LOUVAIN

Belgium

EU Contribution

€ 256 320

UNIVERSITAETSKLINIKUM HEIDELBERG

Germany

EU Contribution

€ 505 576,80

STICHTING VUMC

Netherlands

EU Contribution

€ 265 619,88

ZYTOPROTEC GMBH

Austria

EU Contribution

€ 528 414,48

UNIVERSIDAD AUTONOMA DE MADRID

Spain

EU Contribution

€ 250 904,88

Partners (11)

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INSTITUT DE RECERCA BIOMEDICA DE LLEIDA FUNDACIO PRIVADA DOCTOR PIFARRE

Spain

UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU

Poland

Australian and New Zealand Dialysis and Transplant (ANZDATA) Registry

Australia

NORTH BRISTOL NATIONAL HEALTH SERVICE TRUST

United Kingdom

UNIVERSITEIT GENT

Belgium

FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSIATRIO LA PAZ

Spain

MEDIZINISCHE UNIVERSITAET WIEN

Austria

Kidney Research UK

United Kingdom

FRESENIUS NETCARE GMBH

Germany

EuroPD eV

Germany

NIERSTICHTING NEDERLAND

Netherlands

Project information

Grant agreement ID: 812699

Status

Ongoing project

  • Start date

    1 January 2019

  • End date

    31 December 2022

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 4 021 380

  • EU contribution

    € 4 021 380

Coordinated by:

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Spain