CORDIS
EU research results

CORDIS

English EN
COllaborative Consortium for the early detection of LIver CANcer

COllaborative Consortium for the early detection of LIver CANcer

Objective

Hepatitis B (HBV) and C virus (HCV) are the most important etiologic agents of Hepatocellular carcinoma (HCC), which is the second leading cause of tumour related death in the world. The burden of HCC in developing countries represents a major challenge in global public health for the oncoming decades. Clinically, HCC patients have a very poor prognosis and high 5-year mortality rate except when detected early. As a result, HCC early detection is a critical parameter to anticipate the initiation of a tumour process, but affordable and discriminant diagnostic tools are lacking.
A consortium of European and Third Countries institutions (Peru and Laos) gathered within the project COCLICAN proposes to tackle this issue through the analysis of metabolomics serum profiles of a large cohort of HBV-HBC infected patients to delineate a bunch of molecules predictive of the emergence of liver cancer. The performance of a low-cost and open-source echo-stethoscope connected to a smartphone will also be assessed, to allow early detection of tumorogenesis in health care underserved areas.
This will be possible, thanks to the construction of a sustainable scientific and academic network of engineers, researchers and clinicians mobilised to exchange expertise, skills, technologies, biological material, deployed in three continents: Europe, South America and Asia.
COCLICAN has been designed to improve research collaborations, to reinforce capacities, to enhance knowledge of partners and students involved in the project, but also to raise awareness of policy makers and to participate to the innovation potential improvement at the European and global levels. COCLICAN will therefore respond to the health needs of left behind populations, all around the world.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT

Address

Boulevard De Dunkerque 44 Cs 90009
13572 Marseille

France

Activity type

Research Organisations

EU Contribution

€ 174 800

Participants (5)

Sort alphabetically

Sort by EU Contribution

Expand all

UNIVERSITE PAUL SABATIER TOULOUSE III

France

EU Contribution

€ 96 600

KAUNO TECHNOLOGIJOS UNIVERSITETAS

Lithuania

EU Contribution

€ 32 200

ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS

France

EU Contribution

€ 36 800

UNIVERSITE LIBRE DE BRUXELLES

Belgium

EU Contribution

€ 55 200

FONDATION MERIEUX

France

EU Contribution

€ 55 200

Partners (2)

Sort alphabetically

Expand all

MINISTRY OF HEALTH

INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS-INEN

Project information

Grant agreement ID: 823935

Status

Ongoing project

  • Start date

    1 November 2018

  • End date

    31 October 2021

Funded under:

H2020-EU.1.3.3.

  • Overall budget:

    € 450 800

  • EU contribution

    € 450 800

Coordinated by:

INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT

France