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COllaborative Consortium for the early detection of LIver CANcer

Objective

Hepatitis B (HBV) and C virus (HCV) are the most important etiologic agents of Hepatocellular carcinoma (HCC), which is the second leading cause of tumour related death in the world. The burden of HCC in developing countries represents a major challenge in global public health for the oncoming decades. Clinically, HCC patients have a very poor prognosis and high 5-year mortality rate except when detected early. As a result, HCC early detection is a critical parameter to anticipate the initiation of a tumour process, but affordable and discriminant diagnostic tools are lacking.
A consortium of European and Third Countries institutions (Peru and Laos) gathered within the project COCLICAN proposes to tackle this issue through the analysis of metabolomics serum profiles of a large cohort of HBV-HBC infected patients to delineate a bunch of molecules predictive of the emergence of liver cancer. The performance of a low-cost and open-source echo-stethoscope connected to a smartphone will also be assessed, to allow early detection of tumorogenesis in health care underserved areas.
This will be possible, thanks to the construction of a sustainable scientific and academic network of engineers, researchers and clinicians mobilised to exchange expertise, skills, technologies, biological material, deployed in three continents: Europe, South America and Asia.
COCLICAN has been designed to improve research collaborations, to reinforce capacities, to enhance knowledge of partners and students involved in the project, but also to raise awareness of policy makers and to participate to the innovation potential improvement at the European and global levels. COCLICAN will therefore respond to the health needs of left behind populations, all around the world.

Field of science

  • /medical and health sciences/health sciences/public and environmental health
  • /engineering and technology/electrical engineering, electronic engineering, information engineering/information engineering/telecommunications/mobile phone
  • /social sciences/sociology/demography/mortality
  • /medical and health sciences/clinical medicine/oncology/cancer
  • /medical and health sciences/clinical medicine/oncology/cancer/liver cancer

Call for proposal

H2020-MSCA-RISE-2018
See other projects for this call

Funding Scheme

MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Coordinator

INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT
Address
Boulevard De Dunkerque 44 Cs 90009
13572 Marseille
France
Activity type
Research Organisations
EU contribution
€ 174 800

Participants (5)

UNIVERSITE PAUL SABATIER TOULOUSE III
France
EU contribution
€ 96 600
Address
Route De Narbonne 118
31062 Toulouse Cedex 9
Activity type
Higher or Secondary Education Establishments
KAUNO TECHNOLOGIJOS UNIVERSITETAS
Lithuania
EU contribution
€ 32 200
Address
K Donelaicio 73
44029 Kaunas
Activity type
Higher or Secondary Education Establishments
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
France
EU contribution
€ 36 800
Address
3 Avenue Victoria
75000 Paris
Activity type
Research Organisations
UNIVERSITE LIBRE DE BRUXELLES
Belgium
EU contribution
€ 55 200
Address
Avenue Franklin Roosevelt 50
1050 Bruxelles
Activity type
Higher or Secondary Education Establishments
FONDATION MERIEUX
France
EU contribution
€ 55 200
Address
Rue Bourgelat 17
69227 Lyon
Activity type
Research Organisations

Partners (2)

MINISTRY OF HEALTH
Laos
Address
Samsenthai Road, Ban Thatkhao
856 Lao
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS-INEN
Peru
Address
Av Angamos Este 2520 Urb La Calera De La Merced
Lima
Activity type
Research Organisations