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Glyco-Nanoparticles for Applications in Advance Nanomedicine

Glyco-Nanoparticles for Applications in Advance Nanomedicine

Objective

The advance of nanomedicine requires the development of novel materials with tailored properties, controlled circulation, optimal targeting and therapeutic efficacy after administration. Nanomaterials engineered with glycans offer multiple possibilities for nanomedicine as these biomolecules when arranged on a nanomaterial surface display strong binding to specific receptors while at the same time the glyco coating can restrict unspecific interactions with proteins, helping to avoid the mononuclear phagocyte system and improved biocompatibility in vivo.
The NanoCarb Network will develop novel and well-characterised nanomaterials with synthetic and native N-glycans that will be used for therapeutics and guide development of new drug delivery applications.
The project will train early stage researchers at the interface of nanotechnology and glycosciences, with the overall goal of achieving a new generation of professionals in nanomedicine for a prospective career in both academia and industry.
To achieve this goal a multidisciplinary consortium has been created including universities, research centres and SMEs with broad expertise ranging from nanotechnology, carbohydrate chemistry, glycoprofiling and in vitro – in vivo screening specialists. An ambitious training plan will be implemented including courses, outreach activities, participation in seminar, and workshops for the development of scientific and transferable skills.
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Coordinator

ROYAL COLLEGE OF SURGEONS IN IRELAND

Address

Saint Stephen'S Green 123
2 Dublin

Ireland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 098 737,28

Participants (8)

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THE UNIVERSITY OF WARWICK

United Kingdom

EU Contribution

€ 606 345,12

UNIVERSITA DEGLI STUDI DI MILANO

Italy

EU Contribution

€ 261 499,68

ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE

Spain

EU Contribution

€ 501 809,76

VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.

Belgium

EU Contribution

€ 256 320

LUDGER LIMITED

United Kingdom

EU Contribution

€ 303 172,56

MIDATECH LTD

United Kingdom

ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI

Italy

EU Contribution

€ 522 999,36

MIDATECH PHARMA ESPANA SL

Spain

EU Contribution

€ 501 809,76

Partners (6)

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UNIVERSITEIT HASSELT

FUNDACAO DA FACULDADE DE CIENCIAS E TECNOLOGIA DA UNIVERSIDADE NOVA DE LISBOA.

MJR PHARMJET GMBH

ATTANA AB

HORIZONS UNLEASHED LTD

ACCELOPMENT AG

Project information

Grant agreement ID: 814236

Status

Ongoing project

  • Start date

    1 October 2018

  • End date

    30 September 2022

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 4 052 693,52

  • EU contribution

    € 4 052 693,52

Coordinated by:

ROYAL COLLEGE OF SURGEONS IN IRELAND

Ireland