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Skin Tissue INTegrity under Shear

Objective

The mechanical, chemical and biological properties of human skin may be challenged when in contact with another surface e.g. immobilized persons supported on a bed or in a wheelchair, amputees wearing a prosthesis, and individuals with orthoses or functional medical devices attached to the skin. This can result pressure ulcers, particularly in the elderly and those with comorbidities such as diabetes. Skin condition is also critical during interactions with personal care products such as creams, shavers, grooming devices, therapeutic lamps or massage equipment, which can result in various forms of irritation. The main scientific aim of STINTS is to understand the complex biomechanical and biochemical pathways leading to loss of skin integrity, following the exposure of the skin to prolonged pressure and shear forces that ultimately result in damage at the cellular level. The objective is to reduce the huge societal and financial costs of pressure ulcers by improving (a) the design of more effective preventative aids (mattresses, shoe insoles, incontinence products etc.), (b) early stage diagnosis (non-invasive biomarkers and sensors, and smart materials) and (c) ultrasound therapy. The new understanding of skin behaviour will also be exploited by application to personal care products (razors that cause minimal skin irritation and skin creams with more efficacious skin hydration and barrier properties). These objectives will be achieved by the deployment of experts in multi-scale computer simulation, experimental cellular and tissue biomechanics, biophysical monitoring, sensor design, medical devices and materials, and clinical studies. STINTS will create an ambitious environment of supradisciplinary inter-sectoral research training for early stage researchers that combines the needs for the creative skills of academic and industrial researchers, the entrepreneurial drive of the private sector and clinical innovation.

Call for proposal

H2020-MSCA-ITN-2018
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Coordinator

THE UNIVERSITY OF BIRMINGHAM
Address
Edgbaston
B15 2TT Birmingham
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 303 172,56

Participants (7)

UNIVERSITY OF SOUTHAMPTON
United Kingdom
EU contribution
€ 606 345,12
Address
Highfield
SO17 1BJ Southampton
Activity type
Higher or Secondary Education Establishments
UNILEVER U.K. CENTRAL RESOURCES LIMITED
United Kingdom
EU contribution
€ 303 172,56
Address
Unilever House, Victoria Embankment 100
EC4Y 0DY London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
EU contribution
€ 531 239,76
Address
Groene Loper 3
5612 AE Eindhoven
Activity type
Higher or Secondary Education Establishments
PHILIPS CONSUMER LIFESTYLE BV
Netherlands
EU contribution
€ 265 619,88
Address
High Tech Campus 52
5656 AG Eindhoven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITE GRENOBLE ALPES
France
EU contribution
€ 549 604,08
Address
621 Avenue Centrale
38058 Grenoble
Activity type
Higher or Secondary Education Establishments
TEL AVIV UNIVERSITY
Israel
EU contribution
€ 527 001,84
Address
Ramat Aviv
69978 Tel Aviv
Activity type
Higher or Secondary Education Establishments
UNIVERSITE DE LILLE
France
EU contribution
€ 549 604,08
Address
42 Rue Paul Duez
59800 Lille
Activity type
Higher or Secondary Education Establishments

Partners (8)

APA PARAFRICTA LTD
United Kingdom
Address
Bedford I-lab Stannard Way Priory Business Park
MK44 3RZ Bedford
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ACTRONIKA
France
Address
68 Boulevard De Courcelles
75017 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SCRIPTORIA LTD
United Kingdom
Address
1 The Hayloft 17A Seely Road
SW17 9QP London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SCA Hygiene Products AB
Sweden
Address
Bäckstensgatan 5
SE 405 03 Göteborg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
British Healthcare Trades Association
United Kingdom
Address
Back Church Lane, New Loom House Suite 4.06
E1 1LU London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EUROPEAN PRESSURE ULCER ADVISORY PANEL CHARITY
United Kingdom
Address
University Of Leeds West Yorkshire
LS2 9JT Leeds
Activity type
Other
WOLFEL ENGINEERING GMBH + CO. KG
Germany
Address
Max Planck Strasse 15
97204 Hochberg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
TEXISENSE
France
Address
Rue Evariste Galois
71210 Torcy
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)