Project description DEENESFRITPL New computational tools to leverage shockwave-induced bubbles and their effects on soft matter Ultrasound cavitation, the generation of tiny cavities or bubbles induced by ultrasonic shockwaves, is used in several medical applications. However, the processes of interaction among the shockwaves, bubbles and soft matter are not well understood and can be harmful. With the support of the Marie Skłodowska-Curie Actions programme, the UCOM project will create a training network to explore these processes on the microscale and macroscale using a combined experimental and computational approach. The experimentally validated computational tools will pave the way for innovations with applications not only to medicine but also to surface cleaning, food processing and more. Show the project objective Hide the project objective Objective The pressures and temperatures developing during the interactions of shockwaves with cavitation bubbles and soft matter induce complex phenomena, both at physical and biochemical levels. These have a non- exhaustive range of relevant applications including ultrasound-based therapies, surface cleaning and food processing. Our aim is to explore these processes both in micro and macroscales using experiments and to develop new computational capabilities for their simulations. Measurements will include temperature/ species forming in collapsing bubbles, identifying chemical reactions and possible tissue interaction, such as protein denaturation and agglomeration; tissue cavitation threshold and its control using nanoparticles, allowing development of new cavitation-mimicking-tissue materials extrapolating to actual tissue properties that will be used for in-vitro testing of equipment with minimum collateral damages. Computations will be based on advanced multi-resolution methods coupling fluid flow, chemical reactions and deforming material mechanics solvers, with physically consistent thermodynamic closure models for the involved materials; pressure wave propagation, bubble nucleation and material damage effects will link microscale phenomena to macroscale. Uncertainty quantification techniques will link computations with experimental data. UCOM builds upon the strong foundations of the PIs and their teams in training researchers in computational and experimental methods on cavitation and their strong record to successfully integrate research and technical applications. The final goal of the research and training program is to explore the enormous potential of the new and experimentally validated computational tools to guide breakthrough innovations and high-impact, high-tech technologies ranging across different sectors that all eventually enhance their careers and will be serving the well-being. Fields of science natural sciencesphysical sciencescondensed matter physicssoft matter physicsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsengineering and technologynanotechnologynano-materialsnatural sciencescomputer and information sciencescomputational sciencemultiphysicsnatural sciencesphysical sciencesacousticsultrasound Keywords Cavitation cfd ultrasound simulation cleaning soft materials bubble dynamics Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Topic(s) MSCA-ITN-2018 - Innovative Training Networks Call for proposal H2020-MSCA-ITN-2018 See other projects for this call Funding Scheme MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN) Coordinator CITY UNIVERSITY OF LONDON Net EU contribution € 909 517,68 Address NORTHAMPTON SQUARE EC1V 0HB London United Kingdom See on map Region London Inner London — East Haringey and Islington Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 909 517,68 Participants (7) Sort alphabetically Sort by Net EU contribution Expand all Collapse all TECHNISCHE UNIVERSITAET MUENCHEN Germany Net EU contribution € 252 788,40 Address Arcisstrasse 21 80333 Muenchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 252 788,40 ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE Switzerland Net EU contribution € 364 643,91 Address BATIMENT CE 3316 STATION 1 1015 Lausanne See on map Region Schweiz/Suisse/Svizzera Région lémanique Vaud Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 364 643,91 SORBONNE UNIVERSITE France Net EU contribution € 549 604,08 Address 21 RUE DE L'ECOLE DE MEDECINE 75006 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 549 604,08 UNIVERSITEIT TWENTE Netherlands Net EU contribution € 796 859,64 Address DRIENERLOLAAN 5 7522 NB Enschede See on map Region Oost-Nederland Overijssel Twente Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 796 859,64 INSTITUTE OF CANCER RESEARCH: THE ROYAL CANCER HOSPITAL LBG United Kingdom Net EU contribution € 606 345,12 Address OLD BROMPTON ROAD 123 SW7 3RP London See on map Region London Inner London — West Kensington & Chelsea and Hammersmith & Fulham Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 606 345,12 OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG Germany Net EU contribution € 430 653,13 Address UNIVERSITAETSPLATZ 2 39106 Magdeburg See on map Region Sachsen-Anhalt Sachsen-Anhalt Magdeburg, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 430 653,13 UNIVERSITE DE GENEVE Switzerland Net EU contribution € 281 276,64 Address RUE DU GENERAL DUFOUR 24 1211 Geneve See on map Region Schweiz/Suisse/Svizzera Région lémanique Genève Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 281 276,64 Partners (9) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSITY OF WASHINGTON United States Net EU contribution € 0,00 Address BROOKLYN AVENUE NE 4333 98195 9472 Seattle Wa See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSITY OF MICHIGAN THE REGENTS OF THE UNIVERSITY OF MICHIGAN United States Net EU contribution € 0,00 Address SOUTH STREET 3003 1068 46109 1274 Ann Arbor See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. TSINGHUA UNIVERSITY China Net EU contribution € 0,00 Address QING HUA YUAN 100084 BEIJING See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. NATIONAL UNIVERSITY CORPORATION THEUNIVERSITY OF TOKYO Japan Net EU contribution € 0,00 Address HONGO BUNKYO KU 7 3 1 113 8656 Tokyo See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. AVIGNON UNIVERSITE France Net EU contribution € 0,00 Address RUE LOUIS PASTEUR 74 84029 Avignon Cedex 01 See on map Region Provence-Alpes-Côte d’Azur Provence-Alpes-Côte d’Azur Vaucluse Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. KING'S COLLEGE LONDON United Kingdom Net EU contribution € 0,00 Address STRAND WC2R 2LS London See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. GUYS AND ST THOMAS' NHS FOUNDATIONTRUST United Kingdom Net EU contribution € 0,00 Address Westminster Bridge Road SE1 7EH London See on map Region London Inner London — East Lambeth Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. PRECISION ACOUSTICS LIMITED United Kingdom Net EU contribution € 0,00 Address SOUTH TERRACE - SOUTH STREET 4 DT1 1DE Dorchester See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region South West (England) Dorset and Somerset Dorset Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. DORNIER MEDTECH SYSTEMS GMBH Germany Net EU contribution € 0,00 Address ARGELSRIEDER FELD 7. 82234 Wessling See on map Region Bayern Oberbayern Starnberg Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data
