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Synthetic biology of carbohydrate-binding proteins: engineering protein-carbohydrate interactions for diagnostics and cell targeting

Project description

Exploiting protein-carbohydrate interactions at the cellular level

Cell membranes contain glycolipids and glycoproteins with the sugar moieties extending to the outer surface of the cell, forming a dense layer known as the glycocalyx. The glycocalyx plays a key role in cell attachment and endocytosis, while it may also serve as a biomarker for neoplastic transformation. This emerging role of the glycocalyx indicates that it could be exploited in diagnosis and therapy. The mission of the EU-funded synBIOcarb project is to train the next generation of experts in glycoscience and the engineering of glycoproteins. Apart from providing fundamental knowledge in key biological processes and disease mechanisms, the project will employ synthetic technologies to produce novel molecular complexes with diverse applications.

Coordinator

UNIVERSITY OF LEEDS
Net EU contribution
€ 909 517,68
Address
Woodhouse Lane
LS2 9JT Leeds
United Kingdom

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Region
Yorkshire and the Humber West Yorkshire Leeds
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (8)

ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
Germany
Net EU contribution
€ 505 576,80
Address
Fahnenbergplatz
79098 Freiburg

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Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
Net EU contribution
€ 549 604,08
Address
Rue Michel Ange 3
75794 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
KOBENHAVNS UNIVERSITET

Participation ended

Denmark
Net EU contribution
€ 280 993,00
Address
Norregade 10
1165 Kobenhavn

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Region
Danmark Hovedstaden Byen København
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
ACIB GMBH
Austria
Net EU contribution
€ 528 414,48
Address
Krenngasse 37/2
8010 Graz

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Region
Südösterreich Steiermark Graz
Activity type
Research Organisations
Non-EU contribution
€ 0,00
CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED
Slovakia
Net EU contribution
€ 466 493,76
Address
Dubravska Cesta 9
845 Bratislava

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Region
Slovensko Bratislavský kraj Bratislavský kraj
Activity type
Research Organisations
Non-EU contribution
€ 0,00
GLYCODIAG
France
Net EU contribution
€ 274 802,04
Address
520 Rue Du Chanteloup
45520 Chevilly

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Centre — Val de Loire Centre — Val de Loire Loiret
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ENGENES BIOTECH GMBH
Austria
Net EU contribution
€ 264 207,24
Address
Muthgasse 11/stiege 2/1. Stock
1190 Wien

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Wien Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
DANMARKS TEKNISKE UNIVERSITET
Denmark
Net EU contribution
€ 314 051,00
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby

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Region
Danmark Hovedstaden Københavns omegn
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Partners (6)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

UNIVERSITE D'ORLEANS
France
Net EU contribution
€ 0,00
Address
Chateau De La Source
45067 Orleans Cedex 2

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Region
Centre — Val de Loire Centre — Val de Loire Loiret
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

KAROLINSKA INSTITUTET
Sweden
Net EU contribution
€ 0,00
Address
Nobels Vag 5
17177 Stockholm

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

TECHNISCHE UNIVERSITAET GRAZ
Austria
Net EU contribution
€ 0,00
Address
Rechbauerstrasse 12
8010 Graz

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Region
Südösterreich Steiermark Graz
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

UNIVERSITAET FUER BODENKULTUR WIEN
Austria
Net EU contribution
€ 0,00
Address
Gregor Mendel Strasse 33
1180 Wien

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Region
Wien Wien
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

GLYCOSELECT LTD
Ireland
Net EU contribution
€ 0,00
Address
24 Woodbine Park Blackrock
A94N447 Dublin

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Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

Elicityl SA
France
Net EU contribution
€ 0,00
Address
746 Avenue Ambroise Croizat
38920 Crolles

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Region
Auvergne-Rhône-Alpes Rhône-Alpes Isère
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00