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European Industrial Doctorate for enhancing upstream biopharmaceutical manufacturing process development through single cell analysis

European Industrial Doctorate for enhancing upstream biopharmaceutical manufacturing process development through single cell analysis

Objective

Our ability to utilise biological systems to produce medicines has improved the quality of life for millions of EU citizens. In recent years a new wave of exciting biopharmaceuticals have been discovered with the potential to advance current treatments for a variety of disorders. These new medicines, however, are becoming increasingly complex and difficult to manufacture. Overcoming the inherent heterogeneity of cells grown in vitro to produce effective, uniform and safe biopharmaceuticals is one of the most significant challenges faced by industry today.
The STACCATO European Industrial Doctorate has been specifically designed to strengthen Europe’s innovation capacity and leadership in the BioPharma sector. The consortium will provide exceptional intersectoral training to 11 ESRs through pioneering research focused on harnessing recent advances in single cell analysis to generate and apply a new suite of tools for cell culture process development. ESRs will participate in a specialised training programme to build their proficiency in essential research and industry disciplines. Additional training in professional skills and entrepreneurship will enable ESRs to become future leaders in biopharmaceutical manufacturing science.
STACCATO is composed of an industry leader in instrumentation for cellular analysis, 3 innovative biotechnology SMEs, a leading academic institution and a research conducting biological medicines regulatory agency. The STACCATO EID will immerse all ESRs in highly dynamic industrial environments while receiving supervision from leading academics. A feature of STACCATO is collaboration amongst experts in the production of different biopharmaceuticals such as therapeutic proteins and CAR T cell therapy. All ESRs will receive unparalleled exposure to pan-biopharmaceutical manufacturing challenges to foster collaboration, catalyse synergies across the network and ultimately create a truly unique training experience.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

National Institute for Bioprocessing Research and Training Ltd

Address

Fosters Avenue Mount Merrion
4 Blackrock Dublin

Ireland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 824 052,96

Participants (5)

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BECTON DICKINSON RESEARCH CENTRE IRELAND LIMITED

Ireland

EU Contribution

€ 274 684,32

INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA

Portugal

EU Contribution

€ 475 440,48

TILT BIOTHERAPEUTICS OY

Finland

EU Contribution

€ 280 805,76

KUNGLIGA TEKNISKA HOEGSKOLAN

Sweden

EU Contribution

€ 563 965,92

BUNDESINSTITUT FUR IMPFSTOFFE UND BIOMEDIZINISCHE ARZNEIMITTEL

Germany

EU Contribution

€ 505 576,80

Partners (10)

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SPIBER TECHNOLOGIES AB

MEIRAGTX UK II LTD

Horizon Discovery Limited

Cobra Biopharma Matfors AB

AVECTAS LIMITED

ACCELOPMENT AG

UNIVERSIDADE NOVA DE LISBOA

HELSINGIN YLIOPISTO

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN

TECHNISCHE UNIVERSITAT DARMSTADT

Project information

Grant agreement ID: 813453

Status

Ongoing project

  • Start date

    1 January 2019

  • End date

    31 December 2022

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 2 924 526,24

  • EU contribution

    € 2 924 526,24

Coordinated by:

National Institute for Bioprocessing Research and Training Ltd

Ireland