CORDIS
EU research results

CORDIS

English EN
conect4children (COllaborative Network for European Clinical Trials For Children)

conect4children (COllaborative Network for European Clinical Trials For Children)

Objective

Paediatric medicines development is embedded in the European policy, legislation and in the work of the pharmaceutical industry but currently the potential of this effort is not realised.
The conect4children (c4c) project will address the critical problems with the design, implementation and operational conduct of paediatric clinical trials, for example the fragmented and redundant efforts between sponsors, sites and countries.
This project will generate a sustainable infrastructure that optimises the delivery of clinical trials in children through: a) a single point of contact for all sponsors, sites and investigators; b) efficient implementation of trials adopting consistent approaches, aligned quality standards and coordination of sites at national and international level; c) collaboration with specialist networks; d) high quality input to study design and preparation through rigorous strategic and operational feasibility assessment and e) the promotion of innovative methodologies.
The project will be managed according to IMI2 best practice with a dedicated communications effort. The clinical trials infrastructure will be setup, implemented and tested by implementing 3-4 industry and at least 1 non-industry proof-of-viability studies. Expert advice groups will promote innovative methodologies and engagement with regulators. The business model for a sustainable infrastructure will be based on the European landscape of paediatric networks and available trial sites, the evaluation of services needs of sponsors of all kinds, and will be informed by the proof-of-viability studies. Supporting activities will include: data management (data about the trials and the network, including performance metrics for network management and promotion; handling trial data for non-industry sponsors; support for common data dictionaries); education and training.
The voices of children, young people and their families will be central to the network.

Coordinator

FONDAZIONE PENTA-FOR THE TREATMENT AND CARE OF CHILDREN WITH HIV-ONLUS

Address

Corso Stati Uniti 4
35127 Padova

Italy

Activity type

Research Organisations

EU Contribution

€ 34 011 250

Participants (42)

Sort alphabetically

Sort by EU Contribution

Expand all

THE UNIVERSITY OF LIVERPOOL

United Kingdom

EU Contribution

€ 4 190 000

OSPEDALE PEDIATRICO BAMBINO GESU

Italy

EU Contribution

€ 2 640 250

EURORDIS - EUROPEAN ORGANISATION FOR RARE DISEASES ASSOCIATION

France

EU Contribution

€ 578 750

EUROPEAN CYSTIC FIBROSIS SOCIETY

Denmark

EU Contribution

€ 168 750

STICHTING KATHOLIEKE UNIVERSITEIT

Netherlands

EU Contribution

€ 2 268 750

SWISS CLINICAL TRIAL ORGANISATION

Switzerland

EU Contribution

€ 547 500

Associação para Investigação e Desenvolvimento da Faculdade de Medicina

Portugal

EU Contribution

€ 647 500

ISTITUTO GIANNINA GASLINI

Italy

EU Contribution

€ 571 250

UNIVERSITY COLLEGE LONDON

United Kingdom

EU Contribution

€ 535 000

SIOP EUROPE ASBL

Belgium

EU Contribution

€ 892 500

TARTU ULIKOOL

Estonia

EU Contribution

€ 1 174 750

OKIDS GMBH

Austria

EU Contribution

€ 573 750

UNIVERSITY OF NEWCASTLE UPON TYNE

United Kingdom

EU Contribution

€ 1 602 500

UNIVERSITEIT GENT

Belgium

EU Contribution

€ 966 250

UNIVERSITATSKLINIKUM HEIDELBERG

Germany

EU Contribution

€ 218 750

ARISTOTELIO PANEPISTIMIO THESSALONIKIS

Greece

EU Contribution

€ 647 500

INSTYTUT POMNIK CENTRUM ZDROWIA DZIECKA

Poland

EU Contribution

€ 647 500

HELSE BERGEN HF*HAUKELAND UNIVERSITY HOSPITAL

Norway

EU Contribution

€ 517 500

ECNP RESEARCH AND SCHOLARSHIP STICHTING (DE ECNP RESEARCH AND SCHOLARSHIP FOUNDATION)

Netherlands

EU Contribution

€ 540 000

ROBERT BOSCH GESELLSCHAFT FUR MEDIZINISCHE FORSCHUNG MBH

Germany

EU Contribution

€ 1 452 500

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK

Ireland

EU Contribution

€ 744 750

KAROLINSKA INSTITUTET

Sweden

EU Contribution

€ 504 250

FUNDACIO SANT JOAN DE DEU

Spain

EU Contribution

€ 1 098 500

SERVIZO GALEGO DE SAUDE

Spain

EU Contribution

€ 1 871 250

GYERMEKGYOGYASZATI KLINIKAI VIZSGALOI HALOZAT

Hungary

EU Contribution

€ 511 250

FONDAZIONE PER LA RICERCA FARMACOLOGICA GIANNI BENZI ONLUS

Italy

EU Contribution

€ 2 103 750

ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK

France

EU Contribution

€ 347 500

HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ

Finland

EU Contribution

€ 1 401 250

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

EU Contribution

€ 1 742 500

HELIOS DR. HORST SCHMIDT KLINIKEN WIESBADEN GMBH

Germany

EU Contribution

€ 410 000

ARSENAL.IT - CENTRO VENETO RICERCAE INNOVAZIONE PER LA SANITA DIGITALE

Italy

EU Contribution

€ 187 500

UNIVERZITA KARLOVA

Czechia

EU Contribution

€ 685 000

JANSSEN PHARMACEUTICA NV

Belgium

Bayer

Germany

SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT

France

Eli Lilly and Company Limited

United Kingdom

UCB BIOPHARMA SPRL

Belgium

NOVARTIS PHARMA AG

Switzerland

INSTITUT DE RECHERCHES INTERNATIONALES SERVIER

France

GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD.

United Kingdom

PFIZER LIMITED

United Kingdom

F. HOFFMANN-LA ROCHE AG

Switzerland

Project information

Grant agreement ID: 777389

Status

Ongoing project

  • Start date

    1 May 2018

  • End date

    30 April 2024

Funded under:

H2020-EU.3.1.7.

  • Overall budget:

    € 140 496 816

  • EU contribution

    € 67 000 000

Coordinated by:

FONDAZIONE PENTA-FOR THE TREATMENT AND CARE OF CHILDREN WITH HIV-ONLUS

Italy