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A Novel Detection protocols for REliable prostate cancer Assays

A Novel Detection protocols for REliable prostate cancer Assays

Objective

The technology validation was successfully completed indicating a great commercial potential, and the innovative and inventive aspects of the assay platform are now covered by the filed priority European Patent Office (EPO) patent applications. Validated glycoprofiling of the proteins now uses lectins in a format, fully compatible with clinical PSA assay kits. This PoC grant focuses on 1. Pre-clinical retrospective validation of the early stage biomarker of prostate cancer (PCa) and 2. Commercialisation of the PCa diagnostics kit. Pre-clinical (60 human serum samples) is ongoing and retrospective validation study (450 human serum samples) of the assay will be performed by statistical analysis using a receiver operating characteristic (ROC) curve. The PoC describes all steps, which have been developed so far and all necessary steps, which need to be done for retrospective validation study, product development and commercialisation through our newly incorporated start-up Glycanostics Ltd. (www.glycanostics.com). We will provide PCa diagnostic test resulting in a second opinion to guide the right decision if the biopsy is needed. This will avoid the needless and unreliable biopsies and in the future rival an inaccurate PSA testing.
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Host institution

CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED

Address

Dubravska Cesta 9
845 Bratislava

Slovakia

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 87 500

Beneficiaries (2)

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CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED

Slovakia

EU Contribution

€ 87 500

GLYCANOSTICS SRO

Slovakia

EU Contribution

€ 61 999,93

Project information

Grant agreement ID: 825586

Status

Ongoing project

  • Start date

    1 December 2018

  • End date

    31 May 2020

Funded under:

H2020-EU.1.1.

  • Overall budget:

    € 149 499,93

  • EU contribution

    € 149 499,93

Hosted by:

CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED

Slovakia