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HEalth data LInkage for ClinicAL benefit

Objective

European researchers have made leading contributions to the large genomic, transcriptomic and clinical datasets from patients with chronic diseases. Advances in information science provide unprecedented opportunities for using these datasets to elucidate the complex biology of these disorders, its influence by environmental triggers, and to personalise their management. Currently, exploitation of these opportunities is limited by a shortage of researchers with the required informatics skills and knowledge of requisite data protection principles. HELICAL addresses this unmet need by developing a trans-sectoral and interdisciplinary training programme that builds on the expertise and existing collaborations of its partners. It provides 15 early stage researchers with training in analysis of large datasets, using autoimmune vasculitis as a paradigm as it is scalable, and as comprehensive biological and clinical datasets are already available. The HELICAL training program focuses on three complementary areas: application of informatics to such datasets to gain new biological insights; translation of these into practical clinical outputs and management of ethical constraints imposed on such studies. The programme will be delivered through a multidisciplinary, trans-sectoral partnership of Academic and Industry researchers with expertise in basic biomedical research, epidemiology, statistics, machine learning, health data governance and ethics. Therefore, HELICAL exploits recent advances in data science to link research datasets with longitudinal healthcare records, based on the robust ethical foundation required for linkage studies using near-patient data, to address key experimental questions. The results will have obvious potential for transforming healthcare in the field of autoimmune disease. The training provided addresses a key skills gap in the European workforce and should make the ESR eminently employable in academic, industrial and clinical sectors.

Field of science

  • /social sciences/media and communications/information science
  • /natural sciences/computer and information sciences/data science
  • /natural sciences/computer and information sciences/computer security/data protection
  • /natural sciences/computer and information sciences/artificial intelligence/machine learning

Call for proposal

H2020-MSCA-ITN-2018
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Address
College Green
2 Dublin
Ireland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 549 368,64

Participants (13)

UNIVERSITE DE PARIS
France
EU contribution
€ 274 802,04
Address
85 Bd Saint Germain
75006 Paris
Activity type
Higher or Secondary Education Establishments
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain
EU contribution
€ 250 904,88
Address
C Rossello 132 Planta 05
08036 Barcelona
Activity type
Research Organisations
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 250 904,88
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
UNIVERSITY OF LEEDS
United Kingdom
EU contribution
€ 303 172,56
Address
Woodhouse Lane
LS2 9JT Leeds
Activity type
Higher or Secondary Education Establishments
CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER
Spain
EU contribution
€ 250 904,88
Address
Calle Rossello 149 Puerta Bjs
08036 Barcelona
Activity type
Other
MEDIZINISCHE UNIVERSITAET WIEN
Austria
EU contribution
€ 264 207,24
Address
Spitalgasse 23
1090 Wien
Activity type
Higher or Secondary Education Establishments
KUNGLIGA TEKNISKA HOEGSKOLAN
Sweden
EU contribution
€ 281 982,96
Address
Brinellvagen 8
100 44 Stockholm
Activity type
Higher or Secondary Education Establishments
IBM IRELAND LIMITED
Ireland
EU contribution
€ 274 684,32
Address
Ibm House, Shelbourne Road
Dublin 4 Ballsbridge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ANAXOMICS BIOTECH SL
Spain
EU contribution
€ 250 904,88
Address
Calle Diputacio 237, P 1 Pta 1
08007 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
TISSUEGNOSTICS GMBH
Austria
EU contribution
€ 264 207,24
Address
Taborstrasse 10/2
1020 Vienna
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FIRALIS
France
EU contribution
€ 274 802,04
Address
Rue Du Fort 35
68330 Huningue
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE EUROPEAN INSTITUTE FOR INNOVATION THROUGH HEALTH DATA
Belgium
EU contribution
€ 256 320
Address
Oude Mechelsestraat 165
1853 Strombeek-bever
Activity type
Research Organisations
UNIVERSITY OF GLASGOW
United Kingdom
EU contribution
€ 303 172,56
Address
University Avenue
G12 8QQ Glasgow
Activity type
Higher or Secondary Education Establishments

Partners (10)

UNIVERSITY OF NEWCASTLE UPON TYNE
United Kingdom
Address
Kings Gate
NE1 7RU Newcastle Upon Tyne
Activity type
Higher or Secondary Education Establishments
UPPSALA UNIVERSITET
Sweden
Address
Von Kraemers Alle 4
751 05 Uppsala
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT GENT
Belgium
Address
Sint Pietersnieuwstraat 25
9000 Gent
Activity type
Higher or Secondary Education Establishments
UNIVERZITA KARLOVA
Czechia
Address
Ovocny Trh 560/5
116 36 Praha 1
Activity type
Higher or Secondary Education Establishments
UNIVERSIDAD AUTONOMA DE BARCELONA
Spain
Address
Calle Campus Universitario Sn Cerdanyola V
08290 Cerdanyola Del Valles
Activity type
Higher or Secondary Education Establishments
FUNDACION INSTITUTO DE INVESTIGACION MARQUES DE VALDECILLA
Spain
Address
Avenida Cardenal Herrera Oria S N
39011 Santander
Activity type
Research Organisations
EAGLE GENOMICS LIMITED
United Kingdom
Address
Biodata Innovation Centre, Wellcome Genome Campus,
CB10 1DR Cambridge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITAT DE BARCELONA
Spain
Address
Gran Via De Les Corts Catalanes 585
08007 Barcelona
Activity type
Higher or Secondary Education Establishments
L.A SANTE, EPIDEMIOLOGIE, EVALUATION ET RECHERCHE L.A.S.E.R.
France
Address
Immeuble Cit 3 Rue De L'arivee
75015 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PATIENTMPOWER LIMITED
Ireland
Address
Digital Hub, Thomas Street
D08P X8H Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)