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Genetics of Individuality

Project description

Sources of phenotypic variation in complex vertebrates

The goal of the EU-funded IndiGene project is the in-depth study and characterisation of the sources of variation resulting in phenotype variability in complex vertebrates. The project will characterise the genetic and environmental sources of variation and individual stochastic variation occurring even in fixed genetic and environmental conditions. Researchers selected the medaka fish (Japanese rice fish) as a model, and inbred and performed whole-genome sequencing of a panel of 111 diverse individual medaka from a single location. Now they plan to study the phenotypes of these fish using a high-replication structure, ranging from organism to molecular phenotypes. The data will be analysed using state-of-the-art methods to partition variation between genetic, environmental and stochastic components and their interactions.

Call for proposal

ERC-2018-SyG
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Host institution

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Address
Meyerhofstrasse 1
69117 Heidelberg
Germany
Activity type
Research Organisations
EU contribution
€ 1 668 988

Beneficiaries (3)

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 1 668 988
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany
EU contribution
€ 4 003 625
Address
Seminarstrasse 2
69117 Heidelberg
Activity type
Higher or Secondary Education Establishments
KARLSRUHER INSTITUT FUER TECHNOLOGIE
Germany
EU contribution
€ 600 000
Address
Kaiserstrasse 12
76131 Karlsruhe
Activity type
Higher or Secondary Education Establishments