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Genetics of Individuality

Project description

Sources of phenotypic variation in complex vertebrates

The goal of the EU-funded IndiGene project is the in-depth study and characterisation of the sources of variation resulting in phenotype variability in complex vertebrates. The project will characterise the genetic and environmental sources of variation and individual stochastic variation occurring even in fixed genetic and environmental conditions. Researchers selected the medaka fish (Japanese rice fish) as a model, and inbred and performed whole-genome sequencing of a panel of 111 diverse individual medaka from a single location. Now they plan to study the phenotypes of these fish using a high-replication structure, ranging from organism to molecular phenotypes. The data will be analysed using state-of-the-art methods to partition variation between genetic, environmental and stochastic components and their interactions.

Host institution

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Net EU contribution
€ 837 261,00
Address
Meyerhofstrasse 1
69117 Heidelberg
Germany

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Other funding
€ 837 261,00

Beneficiaries (4)

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
Net EU contribution
€ 837 261,00
Address
Meyerhofstrasse 1
69117 Heidelberg

See on map

Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Other funding
€ 837 261,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

GENOME RESEARCH LIMITED
United Kingdom
Net EU contribution
€ 831 727,00
Address
The Gibbs Building, Euston Road 215
NW1 2BE London

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Region
London Inner London — West Camden and City of London
Activity type
Research Organisations
Other funding
€ 831 727,00
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany
Net EU contribution
€ 4 003 625,00
Address
Seminarstrasse 2
69117 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 4 003 625,00
KARLSRUHER INSTITUT FUER TECHNOLOGIE
Germany
Net EU contribution
€ 600 000,00
Address
Kaiserstrasse 12
76131 Karlsruhe

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Region
Baden-Württemberg Karlsruhe Karlsruhe, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 600 000,00