Project description
Novel testing methods for metabolism-disrupting chemicals
Metabolism-disrupting chemicals (MDCs) are natural and anthropogenic chemicals that disrupt the metabolism and ultimately result in obesity and diabetes. The EU-funded GOLIATH project aims to develop an integrated approach for testing and assessing MDCs. Researchers will focus on the main cellular targets of metabolic disruption and develop predictive models as well as toxicity screening assays. Combined with omics data, these tools will help decipher the endocrine mode of action and the adverse effects of MDCs on human health. The GOLIATH test methods have the potential to be exploited for regulatory use, leading to much anticipated guidelines.
Fields of science
Programme(s)
Topic(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
UNIVERSITEIT UTRECHT
Net EU contribution
€ 1 268 269,88
Address
Heidelberglaan 8
3584 CS Utrecht
Netherlands
3584 CS Utrecht
Netherlands
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Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Participants (15)
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France
Net EU contribution
€ 798 786,25
Address
147 Rue De L'universite
75007 Paris Cedex 07
75007 Paris Cedex 07
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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Department of Health
United Kingdom
Net EU contribution
€ 459 104,53
Address
Quarry House, Quarry Hill
LS2 7UE Leeds
LS2 7UE Leeds
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Region
Yorkshire and the Humber West Yorkshire Leeds
Activity type
Research Organisations
Non-EU contribution
€ 0,00
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 1 077 695,00
Address
Rue De Tolbiac 101
75654 Paris
75654 Paris
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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
KAROLINSKA INSTITUTET
Sweden
Net EU contribution
€ 402 500,00
Address
Nobels Vag 5
17177 Stockholm
17177 Stockholm
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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE
Spain
Net EU contribution
€ 672 862,50
Address
Avenida De La Universidad S-n
03202 Elche
03202 Elche
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Region
Este Comunitat Valenciana Alicante/Alacant
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL
France
Net EU contribution
€ 134 250,00
Address
14 Rue Pierre Et Marie Curie
94700 Maisons Alfort
94700 Maisons Alfort
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Region
Ile-de-France Ile-de-France Val-de-Marne
Activity type
Research Organisations
Non-EU contribution
€ 0,00
LINKOPINGS UNIVERSITET
Sweden
Net EU contribution
€ 338 287,50
Address
Campus Valla
581 83 Linkoping
581 83 Linkoping
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Region
Östra Sverige Östra Mellansverige Östergötlands län
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.
Belgium
Net EU contribution
€ 137 510,00
Address
Boeretang 200
2400 Mol
2400 Mol
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Region
Vlaams Gewest Prov. Antwerpen Arr. Turnhout
Activity type
Research Organisations
Non-EU contribution
€ 0,00
BRUNEL UNIVERSITY LONDON
United Kingdom
Net EU contribution
€ 261 946,25
Address
Kingston Lane
UB8 3PH Uxbridge
UB8 3PH Uxbridge
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Region
London Outer London — West and North West Harrow and Hillingdon
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Participation ended
United Kingdom
Net EU contribution
€ 0,00
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
CB2 1TN Cambridge
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Region
East of England East Anglia Cambridgeshire CC
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
United States
Net EU contribution
€ 339 596,84
Address
Franklin Street 1111 12 Floor
94607 Oakland Ca
94607 Oakland Ca
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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
BIOPREDIC INTERNATIONAL SARL
France
Net EU contribution
€ 243 750,00
Address
Parc D'activite De La Breteche Batiment A4
35760 Saint Gregoire
35760 Saint Gregoire
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SME
YesThe organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Region
Bretagne Bretagne Ille-et-Vilaine
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
HOFFMANN SEBASTIAN
Germany
Net EU contribution
€ 75 000,00
Address
Stembergring 15
33106 Paderborn
33106 Paderborn
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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UMEA UNIVERSITET
Sweden
Net EU contribution
€ 303 750,00
Address
Universitetomradet
901 87 Umea
901 87 Umea
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Region
Norra Sverige Övre Norrland Västerbottens län
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
Net EU contribution
€ 248 525,00
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
SW7 2AZ London
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Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00