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Biocatalytic Methyltransferase Cascades

Objective

The goal of this project is to develop a general system for preparative enzyme-catalyzed methylation reactions. Selective methylation of complex molecules can be challenging for synthetic chemistry. Given the exquisite chemo-, regio- and stereoselectivities of enzyme catalysis we believe that biocatalysis presents a powerful alternative for commercial production of pharmaceuticals and fine chemicals. In this project we demonstrate the applicability and commercial viability of a novel enzyme-based technology to preparative methylation reactions.

Field of science

  • /engineering and technology/industrial biotechnology/bioprocessing technologies/biocatalysis
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes

Call for proposal

ERC-2018-PoC
See other projects for this call

Funding Scheme

ERC-POC - Proof of Concept Grant

Host institution

UNIVERSITAT BASEL
Address
Petersplatz 1
4051 Basel
Switzerland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 149 760

Beneficiaries (1)

UNIVERSITAT BASEL
Switzerland
EU contribution
€ 149 760
Address
Petersplatz 1
4051 Basel
Activity type
Higher or Secondary Education Establishments