CORDIS
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CORDIS

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Communicating Vesicles

Project information

Grant agreement ID: 837706

Status

Ongoing project

  • Start date

    8 April 2019

  • End date

    7 April 2021

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 212 933,76

  • EU contribution

    € 212 933,76

Coordinated by:

THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE

United Kingdom

Objective

Networks constituted from single components able to communicate with each other in a controlled manner are at the basis of every phenomenon occurring in the world around us. Understanding and controlling information transmission processes represents one of the greatest challenges for modern scientists. I propose to develop an understanding of the working principles of complex information processing networks by using an artificial system that resembles Nature’s cell-based communication systems. Inspired by the cascade processes occurring in Nature such as the second messenger system and extracellular messenger release, “CoVes” will be based on responsive Vesicles able to Communicate in a specific and targeted manner due to different input signals. Vesicles will be equipped with a series of synthetic transducers that respond to orthogonal external chemical stimuli. Transmembrane signalling will be coupled with internal chemical messenger release leading to communication between vesicles in an information network. The working principles of the novel multi-component ensembles will be investigated leading to systems capable of transmitting information under different diffusion conditions and paving the way for novel communication mechanisms. The accurate and reliable prediction of communication processes will lead to vesicle ensembles able to store and transfer information using orthogonal stimuli which will be crucial for the development of bio-inspired nanotechnology, such as interfaces for communication with cellular systems. The accomplishments achieved through CoVes will make chemistry not only the science of matter transformation, but also the science of information storage, elaboration and transfer.

Coordinator

THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE

Address

Trinity Lane The Old Schools
Cb2 1tn Cambridge

United Kingdom

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 212 933,76

Project information

Grant agreement ID: 837706

Status

Ongoing project

  • Start date

    8 April 2019

  • End date

    7 April 2021

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 212 933,76

  • EU contribution

    € 212 933,76

Coordinated by:

THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE

United Kingdom