CORDIS
EU research results

CORDIS

English EN

Single-cell genomics to comprehensively understand healthy B-cell maturation and transformation to chronic lymphocytic leukemia

Project information

Grant agreement ID: 810287

Status

Ongoing project

  • Start date

    1 April 2019

  • End date

    31 March 2024

Funded under:

H2020-EU.1.1.

  • Overall budget:

    € 8 333 331

  • EU contribution

    € 8 333 331

Hosted by:

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

Project description

English EN

Mapping the path from immune cell to cancer

B-cells are highly dynamic lymphocytes in the immune system. When B-cells bind with an antigen, a chemical signal tells them to divide many times, resulting in an army of B-cells that ultimately produce thousands of antibodies in seconds. B-cells are also at the root of chronic lymphocytic leukaemia (CLL), the most common form of leukaemia in Western countries. CLL is characterised by abnormal growth and proliferation of neoplastic B-cells. EU-funded scientists are studying the maturation of thousands of healthy and diseased B-cells with the ambitious goal of characterising CLL molecular biology throughout the course of the disease process.

Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Host institution

FUNDACIO CENTRE DE REGULACIO GENOMICA

Address

Carrer Doctor Aiguader 88
08003 Barcelona

Spain

Activity type

Research Organisations

EU Contribution

€ 5 451 231

Beneficiaries (2)

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

EU Contribution

€ 5 451 231

CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER

Spain

EU Contribution

€ 2 882 100

Project information

Grant agreement ID: 810287

Status

Ongoing project

  • Start date

    1 April 2019

  • End date

    31 March 2024

Funded under:

H2020-EU.1.1.

  • Overall budget:

    € 8 333 331

  • EU contribution

    € 8 333 331

Hosted by:

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain