CORDIS
EU research results

CORDIS

English EN

High-performance biomechanical model of combined immunotherapy and anti-angiogenic cancer treatment

Project information

Grant agreement ID: 867455

Status

Ongoing project

  • Start date

    17 June 2019

  • End date

    16 June 2021

Funded under:

H2020-EU.4.

  • Overall budget:

    € 145 941,12

  • EU contribution

    € 145 941,12

Coordinated by:

UNIVERSITY OF CYPRUS

Cyprus

Project description

English EN

The vascular road to effective immunotherapy

Tumour growth and treatment delivery are highly dependent on vascularisation of the tumour itself. Tumour cells produce molecules that encourage angiogenesis, supporting their rapid growth and transition from benign tumours to malignant. These molecules also make the blood vessels leaky and porous. The latter helps tumour cells to enter the bloodstream and spread while concurrently compromising delivery of chemo- and immuno-therapies. EU-funded scientists are developing computational models of tumour microenvironments and repair of vascular abnormalities to better understand the effects of optimised vascular perfusion on promising immunotherapies. Predictions will be tested in experimental models.

Coordinator

UNIVERSITY OF CYPRUS

Address

Kallipoleos Street 75
1678 Nicosia

Cyprus

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 145 941,12

Project information

Grant agreement ID: 867455

Status

Ongoing project

  • Start date

    17 June 2019

  • End date

    16 June 2021

Funded under:

H2020-EU.4.

  • Overall budget:

    € 145 941,12

  • EU contribution

    € 145 941,12

Coordinated by:

UNIVERSITY OF CYPRUS

Cyprus