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Translational Safety Biomarker Pipeline (TransBioLine): Enabling development and implementation of novel safety biomarkers in clinical trials and diagnosis of disease

Project description

Novel safety biomarkers for drug development

Testing the safety of drugs is the most important aspect in the drug development pipeline. Although various safety biomarkers have been proposed, substantial sample sizes are required for their validation. The EU-funded TransBioLine project will capitalise on existing data, resources and international collaborations to establish robust biomarkers for use in drug development. Researchers will also develop and validate assays for new safety biomarkers and implement circulating miRNAs as tissue- and mechanism-specific diagnostic tools. Ultimately, the aim is to obtain approval of safety biomarkers as qualified drug development tools by key regulatory authorities such as the EMA and FDA.

Call for proposal

H2020-JTI-IMI2-2017-13-two-stage
See other projects for this call

Funding Scheme

IMI2-RIA - Research and Innovation action

Coordinator

UNIVERSITAT ZURICH
Address
Ramistrasse 71
8006 Zurich
Switzerland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 389 381

Participants (28)

UNIVERSIDAD DE MALAGA
Spain
EU contribution
€ 246 452
Address
Avda Cervantes, Num. 2
29016 Malaga
Activity type
Higher or Secondary Education Establishments
INFORMATION TECHNOLOGY FOR TRANSLATIONAL MEDICINE (ITTM) SA
Luxembourg
EU contribution
€ 624 125
Address
9 Avenue Des Hauts-forneaux
4362 Esch-sur-alzette
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LANDSPITALI UNIVERSITY HOSPITAL
Iceland
EU contribution
€ 87 325
Address
Eiriksgata 5
101 Reykjavik
Activity type
Higher or Secondary Education Establishments
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 443 450
Address
Geschwister Scholl Platz 1
80539 Muenchen
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
EU contribution
€ 832 700
Address
University Park
NG7 2RD Nottingham
Activity type
Higher or Secondary Education Establishments
UNIVERSIDAD DE SALAMANCA
Spain
EU contribution
€ 69 500
Address
Calle Patio De Escuelas 1
37008 Salamanca
Activity type
Higher or Secondary Education Establishments
INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU FUNDACION
Spain
EU contribution
€ 182 600
Address
C Sant Quinti 77-79
08041 Barcelona
Activity type
Research Organisations
TAMIRNA GMBH
Austria
EU contribution
€ 1 231 000
Address
Leberstrasse 20/8
1110 Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SIGNATOPE GMBH
Germany
EU contribution
€ 1 990 000
Address
Markwiesenstr. 55
72770 Reutlingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ABX CRO ADVANCED PHARMACEUTICAL SERVICES FORSCHUNGSGESELLSCHAFT MBH
Germany
EU contribution
€ 1 294 360
Address
Blasewitzer Str 78-80
01307 Dresden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
METAHEPS GMBH
Germany
EU contribution
€ 284 000
Address
Am Klopferspitz 19
82152 Planegg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
France
EU contribution
€ 81 400
Address
3 Avenue Victoria
75000 Paris
Activity type
Research Organisations
SYNAPSE RESEARCH MANAGEMENT PARTNERS SL
Spain
EU contribution
€ 900 000
Address
Calle Velazquez 94 Planta 1
28006 Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 1 386 193,75
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
UNIVERSITY OF NEWCASTLE UPON TYNE
United Kingdom
EU contribution
€ 109 475
Address
Kings Gate
NE1 7RU Newcastle Upon Tyne
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY OF LIVERPOOL
United Kingdom
EU contribution
€ 940 250
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool
Activity type
Higher or Secondary Education Establishments
MLM MEDICAL LABS GMBH
Germany
EU contribution
€ 604 800
Address
Dohrweg 63
41066 Monchengladbach
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITEIT LEIDEN
Netherlands
EU contribution
€ 34 000
Address
Rapenburg 70
2311 EZ Leiden
Activity type
Higher or Secondary Education Establishments
SERVICIO ANDALUZ DE SALUD
Spain
EU contribution
€ 188 946
Address
Avenida De La Constitucion 18
41071 Sevilla
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
PFIZER LIMITED
United Kingdom
EU contribution
€ 0
Address
Ramsgate Road
CT13 9NJ Sandwich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MERCK SHARP & DOHME CORP
United States
EU contribution
€ 0
Address
One Merck Drive
08889 Whitehouse Station Nj
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Eli Lilly and Company Limited
United Kingdom
EU contribution
€ 0
Address
Lilly House, Priestley Road
RG24 9NL Basingstoke
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NOVARTIS PHARMA AG
Switzerland
EU contribution
€ 0
Address
Lichtstrasse 35
4056 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
F. HOFFMANN-LA ROCHE AG
Switzerland
EU contribution
€ 0
Address
Grenzacherstrasse 124
4070 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
JANSSEN PHARMACEUTICA NV
Belgium
EU contribution
€ 0
Address
Turnhoutseweg 30
2340 Beerse
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT
France
EU contribution
€ 0
Address
Pierre Brossolette 1
91380 Chilly Mazarin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE CRITICAL PATH INSTITUTE (C-PATH) NON PROFIT CORPORATION
United States
EU contribution
€ 0
Address
E River Road 1730 200
85718 Tucson Az
Activity type
Other
UNIVERSITAET BERN
Switzerland
EU contribution
€ 80 040
Address
Hochschulstrasse 6
3012 Bern
Activity type
Higher or Secondary Education Establishments