Project description DEENESFRITPL Bone implants with enhanced features Orthopaedic implants are used to replace a missing bone or joint or to support damaged bone. Ideally, these implants must exhibit life-long performance, which translates to implants with functional osseointegration and antibacterial features. For this purpose, the EU-funded EDiMplant project proposes to develop a technique for the surface modification of orthopaedic implants. Researchers wish to fabricate layer surfaces that combine enhanced osteogenic and antibacterial characteristics. Project deliverables will help reduce the incidence of orthopaedic implant failures and improve the quality of life of inflicted individuals who are increasing in numbers due to the ageing population. Show the project objective Hide the project objective Objective Recently, the demand for orthopaedic implants and devices has undertaken rapid growth due to the aging population and its global market is anticipated to reach $66.2B in 2023. To ensure the long-term survival of orthopaedic implants, it is urgent to tailor a multifunctional surface which would simultaneously have enhanced osteogenic and antibacterial properties. Therefore, the aim is to develop a competent surface modification technique which will promote improved osseointegration whilst retaining antimicrobial activity, thus ensuring the life-long performance of implants. A novel surface modification approach will be demonstrated using the specially designed tool electrodes in powder mixed electric discharge machining process for fabrication of modified surface layers exhibiting anti-bacterial and osteogenic characteristics. Exploiting world class facilities at University of Sheffield and a unique multidisciplinary framework; EDiMplant will reach the aim and strengthen the pillars of Horizon 2020. Supervisor(s) with world-leading experience, Dr Gwendolen Reilly, Dr Frederik Claeyssens, Dr Russell Goodall, and Dr Joanna Shepherd, will provide expert training and support to the Fellow in the essential skills inmaterial science, tissue engineering and infection biology, while, Dr Deepak Unune, leading Indian researcher, will bring expertise and novel application of electric discharge machining in surface modifications of implants to the host(s). The high-quality two-way transfer of knowledge required for this project will ensure the research goals of the highest quality are achieved, whilst also presenting a great opportunity to accelerate the academic career of the Fellow. Success would also lead to significant economic and societal impacts for the EU and worldwide, by aiding in the reduced incidence of orthopaedic implant failures. Fields of science natural scienceschemical sciencesinorganic chemistrytransition metalsengineering and technologymechanical engineeringmanufacturing engineeringsubtractive manufacturingmedical and health sciencesmedical biotechnologytissue engineeringmedical and health sciencesclinical medicineorthopaedicsmedical and health sciencesmedical biotechnologyimplants Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2018 - Individual Fellowships Call for proposal H2020-MSCA-IF-2018 See other projects for this call Funding Scheme MSCA-IF-EF-ST - Standard EF Coordinator THE UNIVERSITY OF SHEFFIELD Net EU contribution € 224 933,76 Address FIRTH COURT WESTERN BANK S10 2TN Sheffield United Kingdom See on map Region Yorkshire and the Humber South Yorkshire Sheffield Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 224 933,76
